TumCG Cancer Research Results

TumCG, Tumor cell growth: Click to Expand ⟱
Source:
Type:
Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M).
Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division).


Arthritis, Arthritis: Click to Expand ⟱
Arthritis


Scientific Papers found: Click to Expand⟱
6185- Cuc,    Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics
- Review, Var, NA - Review, Arthritis, NA - Review, AD, NA
*Inflam↓, *antiOx↑, *hepatoP↑, *neuroP↑, *AntiCan↑, *toxicity↝, *BioAv↓, *HO-1↑, *NRF2↑, *NLRP3↑, *SOD↑, *SOD1↑, *ROS↓, *AntiAge↑, *ARE↑, *STAT↓, *NF-kB↓, *neuroG↑, *memory↑, ROS↑, NLRP3↑, CIP2A↓, Akt↓, STAT3↑, VEGFR2↓, DNMTs↓, MAPK↓, YAP/TEAD↓, PI3K↓, Wnt↓, NOTCH↓, TumCCA↑, TumCG↓, TumCP↓, FAK↑, MMP9↓, TumAuto↑, toxicity↝, BioAv↓, Half-Life↝, BioAv↑, selectivity∅,
3929- PTS,    New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects
- Review, Var, NA - Review, Arthritis, NA
*NRF2↑, *BioAv↑, *ROS↓, *Inflam↓, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *hepatoP↑, *neuroP↑, *iNOS↓, *COX2↓, TumMeta↓, SOD2↓, ROS↑, TumCI↓, TumCG↓, HDAC1↓, PTEN↑, BP↓, *GutMicro↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↑, 2,   SOD2↓, 1,  

Cell Death

Akt↓, 1,   MAPK↓, 1,   YAP/TEAD↓, 1,  

Autophagy & Lysosomes

TumAuto↑, 1,  

DNA Damage & Repair

DNMTs↓, 1,  

Cell Cycle & Senescence

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

CIP2A↓, 1,   HDAC1↓, 1,   NOTCH↓, 1,   PI3K↓, 1,   PTEN↑, 1,   STAT3↑, 1,   TumCG↓, 2,   Wnt↓, 1,  

Migration

FAK↑, 1,   MMP9↓, 1,   TumCI↓, 1,   TumCP↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature

VEGFR2↓, 1,  

Protein Aggregation

NLRP3↑, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 1,   Half-Life↝, 1,   selectivity∅, 1,  

Clinical Biomarkers

BP↓, 1,  

Functional Outcomes

toxicity↝, 1,  
Total Targets: 29

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   ARE↑, 1,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 2,   lipid-P↓, 1,   NRF2↑, 2,   ROS↓, 2,   SOD↑, 2,   SOD1↑, 1,  

Cell Death

iNOS↓, 1,  

Proliferation, Differentiation & Cell State

neuroG↑, 1,   STAT↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   Inflam↓, 2,   NF-kB↓, 1,  

Protein Aggregation

NLRP3↑, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 1,  

Clinical Biomarkers

GutMicro↑, 1,  

Functional Outcomes

AntiAge↑, 1,   AntiCan↑, 1,   hepatoP↑, 2,   memory↑, 1,   neuroP↑, 2,   toxicity↝, 1,  
Total Targets: 26

Scientific Paper Hit Count for: TumCG, Tumor cell growth
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:323  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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