RNS Cancer Research Results

RNS, reactive nitrogen species: Click to Expand ⟱
Source:
Type:
Reactive nitrogen species (RNS) are chemically reactive molecules that contain nitrogen and can play significant roles in cellular signaling and homeostasis. Like reactive oxygen species (ROS), RNS can have both beneficial and detrimental effects in the context of cancer.
Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.
Scientific Papers found: Click to Expand⟱
6317- DRE,    The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells
- in-vitro, Melanoma, A375
Apoptosis↑, selectivity↑, Casp8↑, mt-ROS↑, eff↑, *toxicity↓, Diff↑, TumCP↓, chemoPv↑, *ROS↓, *NO↓, *COX2↓, *RNS↓, TumCI↓, MMP2↓, MMP9↓, p‑Src↓, p‑FAK↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

mt-ROS↑, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   Casp8↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Diff↑, 1,   p‑Src↓, 1,  

Migration ⓘ

p‑FAK↓, 1,   MMP2↓, 1,   MMP9↓, 1,   TumCI↓, 1,   TumCP↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

chemoPv↑, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

RNS↓, 1,   ROS↓, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,  

Functional Outcomes ⓘ

toxicity↓, 1,  
Total Targets: 5

Scientific Paper Hit Count for: RNS, reactive nitrogen species
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:39  Cells:%  prod#:%  Target#:276  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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