STAT1 Cancer Research Results

STAT1, Signal transducer and activator of transcription 1: Click to Expand ⟱
Source:
Type:
STAT1 (Signal Transducer and Activator of Transcription 1) is a transcription factor that plays a crucial role in various cellular processes, including immune response, cell growth, and apoptosis.
Unregulated in some cancers.
High STAT1 expression has been associated with improved prognosis and reduced metastasis.
Low STAT1 expression has been linked to poor prognosis and reduced survival.


Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.

Scientific Papers found: Click to Expand⟱
1024- Api,  CUR,    Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects
- vitro+vivo, Melanoma, A375 - in-vitro, Melanoma, A2058 - in-vitro, Melanoma, RPMI-7951
TumCG↓, Apoptosis↑, PD-L1↓, STAT1↓, tumCV↓, T-Cell↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death

Apoptosis↑, 1,  

Transcription & Epigenetics

tumCV↓, 1,  

Proliferation, Differentiation & Cell State

STAT1↓, 1,   TumCG↓, 1,  

Immune & Inflammatory Signaling

PD-L1↓, 1,   T-Cell↑, 1,  

Clinical Biomarkers

PD-L1↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: STAT1, Signal transducer and activator of transcription 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:39  Cells:%  prod#:%  Target#:370  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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