p27 Cancer Research Results
p27, p27kip1: Click to Expand ⟱
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| Type: |
The cyclin-dependent kinase (Cdk) inhibitor p27 regulates cell proliferation, cell motility and apoptosis, and is inactivated through various means in many types of human cancer.
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Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Melanoma, |
MSTO-211H |
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tumCV↓, Apoptosis↑, Sp1/3/4↓, p27↓, P21↓, cycD1/CCND1↓, Mcl-1↓, survivin↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1, Mcl-1↓, 1, p27↓, 1, survivin↓, 1,
Kinase & Signal Transduction ⓘ
Sp1/3/4↓, 1,
Transcription & Epigenetics ⓘ
tumCV↓, 1,
Cell Cycle & Senescence ⓘ
cycD1/CCND1↓, 1, P21↓, 1,
Total Targets: 8
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: p27, p27kip1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:39 Cells:% prod#:% Target#:468 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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