CD44 Cancer Research Results

CD44, CD44: Click to Expand ⟱
Source:
Type:
CD44 represents a common biomarker of cancer stem cells, and promotes epithelial-mesenchymal transition. CD44 is a well-known marker of CSCs and plays important roles in tumor initiation and development.
Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.
Scientific Papers found: Click to Expand⟱
5679- BML,    Bromelain proteinases modulate the cd44 expression on human molt-4/8 leukemia and sk-mel-28 melanoma-cells in-vitro
- in-vitro, Melanoma, SK-MEL-28
CD44↓,
5337- TFdiG,    Theaflavin 3,3'-digallate suppresses metastasis and reduces insulin-like growth factor-1-induced cancer stemness and invasiveness in human melanoma cells
- in-vitro, Melanoma, A375 - in-vitro, Melanoma, A2058
TumCMig↓, TumCI↓, MMPs↓, ALDH↓, CSCs↓, ABCG2↓, CD44↓, CXCR4↓, TumCG↓, angioG↓, TumMeta↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

ALDH↓, 1,   CD44↓, 2,   CSCs↓, 1,   TumCG↓, 1,  

Migration ⓘ

MMPs↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,  

Immune & Inflammatory Signaling ⓘ

CXCR4↓, 1,  

Drug Metabolism & Resistance ⓘ

ABCG2↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CD44, CD44
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:39  Cells:%  prod#:%  Target#:48  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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