PTPN6 Cancer Research Results
PTPN6, SHP1/Protein Tyrosine Phosphatase, Non-Receptor Type 6: Click to Expand ⟱
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Also known as SHP-1 (Src Homology 2 Domain-Containing Phosphatase 1)
SHP-1 (Src homology 2 domain-containing phosphatase-1) is a protein tyrosine phosphatase that plays a crucial role in regulating various cellular processes, including cell signaling, proliferation, and survival. Its expression has been implicated in the development and progression of various types of cancer.
Low SHP-1 expression is associated with poor prognosis, increased tumor size, and lymph node metastasis.
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Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Melanoma, |
U251 |
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in-vitro, |
Melanoma, |
MM.1S |
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STAT3↓, PTEN↑, Apoptosis↑, PTPN6↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1,
Proliferation, Differentiation & Cell State ⓘ
PTEN↑, 1, PTPN6↑, 1, STAT3↓, 1,
Total Targets: 4
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: PTPN6, SHP1/Protein Tyrosine Phosphatase, Non-Receptor Type 6
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:39 Cells:% prod#:% Target#:923 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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