toxicity Cancer Research Results

toxicity, toxicity: Click to Expand ⟱
Source:
Type:
Toxicity
Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.
Scientific Papers found: Click to Expand⟱
5387- AsP,  PacT,    Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy
- in-vivo, Melanoma, B16-F10
Dose↝, TumCG↓, TumCP↓, BioAv↓, BioAv↑, other↑, Apoptosis↑, Bax:Bcl2↑, EPR↑, toxicity↝,
5013- DSF,  Cu,  Z,    Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease
- vitro+vivo, Melanoma, NA - Case Report, Melanoma, NA
P-gp↓, NF-kB↓, ChemoSen↑, angioG↓, TumCG↓, TumMeta↓, Remission↑, toxicity↓, ATF2↓, CREB↓, cycA1/CCNA1↓, TumCG↓, angioG↓, Dose↝, toxicity↝,
7320- Gos,    AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma
- Trial, Melanoma, NA
Bcl-2↓, Mcl-1↓, Apoptosis↑, eff↑, toxicity↝, ORR↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ORR↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CREB↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 2,   ATF2↓, 1,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   Mcl-1↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycA1/CCNA1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 3,  

Migration(tgid=13) ⓘ

TumCP↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   EPR↑, 1,  

Barriers & Transport(tgid=15) ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   ChemoSen↑, 1,   Dose↝, 2,   eff↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Remission↑, 1,   toxicity↓, 1,   toxicity↝, 3,  
Total Targets: 24

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: toxicity, toxicity
1 Ascorbyl Palmitate
1 Paclitaxel/Taxol
1 Disulfiram
1 Copper and Cu NanoParticles
1 Zinc
1 Gossypol/AT-101
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:39  Cells:%  prod#:%  Target#:1025  State#:%  Dir#:4
  wNotes=0  sortOrder:rid,rpid

 

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