toxicity Cancer Research Results
toxicity, toxicity: Click to Expand ⟱
Melanoma, Melanoma Skin Cancer: Click to Expand ⟱
Melanoma is a rare form of skin cancer. It is more likely to invade nearby tissues and spread to other parts of the body than other types of skin cancer.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Lung, |
A549 |
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in-vitro, |
Melanoma, |
WM983B |
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in-vivo, |
NA, |
NA |
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TumCG↓, eff↑, T-Cell↑, p‑IGF-1R↓, p‑Akt↓, PTEN↑, p‑eIF2α↑, OCR↓, ROS↓, ECAR∅, IL1↑, TNF-α↑, IL10↑, IGF-1R↓, eIF2α↑, PTEN↑, TCA↓, Glycolysis↓, selectivity↑, *toxicity∅, Dose∅,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↓, 1,
Mitochondria & Bioenergetics ⓘ
OCR↓, 1,
Core Metabolism/Glycolysis ⓘ
ECAR∅, 1, Glycolysis↓, 1, TCA↓, 1,
Cell Death ⓘ
p‑Akt↓, 1,
Protein Folding & ER Stress ⓘ
eIF2α↑, 1, p‑eIF2α↑, 1,
Proliferation, Differentiation & Cell State ⓘ
IGF-1R↓, 1, p‑IGF-1R↓, 1, PTEN↑, 2, TumCG↓, 1,
Immune & Inflammatory Signaling ⓘ
IL1↑, 1, IL10↑, 1, T-Cell↑, 1, TNF-α↑, 1,
Drug Metabolism & Resistance ⓘ
Dose∅, 1, eff↑, 1, selectivity↑, 1,
Total Targets: 19
Pathway results for Effect on Normal Cells:
Functional Outcomes ⓘ
toxicity∅, 1,
Total Targets: 1
Scientific Paper Hit Count for: toxicity, toxicity
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:39 Cells:% prod#:% Target#:1025 State#:% Dir#:6
wNotes=0 sortOrder:rid,rpid
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