Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
Source:
Type:
Drug dosage vs efficacy, and actual dosage number of research papers.


BC, Breast Cancer: Click to Expand ⟱
Breast Cancer

Scientific Papers found: Click to Expand⟱
6618- Ech,    Kaempferols from Echinacea purpurea demonstrate anti-cancer potential by targeting anexelekto in breast cancer therapy using chemoinformatics approach
- Analysis, BC, NA
AXL↓, Dose?,
7138- GI,    6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways
- vitro+vivo, BC, MDA-MB-231 - in-vitro, Pca, DU145 - in-vitro, Liver, HepG2 - in-vitro, Lung, A549
TumCP↓, TumMeta↓, p‑STAT3↓, JAK2↓, cSrc↓, JNK↑, p38↑, ERK↑, eff↓, ROS↑, cl‑PARP↑, TumCCA↑, Casp8↑, Casp9↑, Casp3↑, eff↑, Bcl-2↑, Bcl-xL↓, survivin↓, MMP9↓, COX2↓, IAP1↓, Dose?,
1534- LT,  Api,  EGCG,  RES,    Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action
- in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468 - in-vitro, PC, Bxpc-3
TumCP↓, Apoptosis↑, eff↓, *toxicity↑, Dose?, eff↓, eff↓,
7388- MFrot,    Magnetoporation and magnetolysis of cancer cells via carbon nanotubes induced by rotating magnetic fields
- in-vitro, BC, MCF7
EPR↑, Dose?,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

ROS↑, 1,  

Cell Death(tgid=5)

Apoptosis↑, 1,   Bcl-2↑, 1,   Bcl-xL↓, 1,   Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 1,   IAP1↓, 1,   JNK↑, 1,   p38↑, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6)

cSrc↓, 1,  

DNA Damage & Repair(tgid=10)

cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

ERK↑, 1,   p‑STAT3↓, 1,  

Migration(tgid=13)

AXL↓, 1,   MMP9↓, 1,   TumCP↓, 2,   TumMeta↓, 1,  

Angiogenesis & Vasculature(tgid=14)

EPR↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 1,   JAK2↓, 1,  

Drug Metabolism & Resistance(tgid=21)

Dose?, 4,   eff↓, 4,   eff↑, 1,  
Total Targets: 26

Pathway results for Effect on Normal Cells:


Functional Outcomes(tgid=23)

toxicity↑, 1,  
Total Targets: 1

Scientific Paper Hit Count for: Dose, Dosage
1 Echinacea
1 Ginger/6-Shogaol/Gingerol
1 Luteolin
1 Apigenin (mainly Parsley)
1 EGCG (Epigallocatechin Gallate)
1 Resveratrol
1 Magnetic Field Rotating
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:0
wNotes=0 sortOrder:rid,rpid

 

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