Dose Cancer Research Results
Dose, Dosage: Click to Expand ⟱
| Source: |
| Type: |
Drug dosage vs efficacy, and actual dosage number of research papers.
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BC, Breast Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
AXL↓, Dose?,
| - |
vitro+vivo, |
BC, |
MDA-MB-231 |
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- |
in-vitro, |
Pca, |
DU145 |
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- |
in-vitro, |
Liver, |
HepG2 |
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- |
in-vitro, |
Lung, |
A549 |
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TumCP↓, TumMeta↓, p‑STAT3↓, JAK2↓, cSrc↓, JNK↑, p38↑, ERK↑, eff↓, ROS↑, cl‑PARP↑, TumCCA↑, Casp8↑, Casp9↑, Casp3↑, eff↑, Bcl-2↑, Bcl-xL↓, survivin↓, MMP9↓, COX2↓, IAP1↓, Dose?,
| - |
in-vitro, |
Nor, |
MCF10 |
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- |
in-vitro, |
BC, |
MDA-MB-231 |
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- |
in-vitro, |
BC, |
MDA-MB-468 |
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- |
in-vitro, |
PC, |
Bxpc-3 |
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TumCP↓, Apoptosis↑, eff↓, *toxicity↑, Dose?, eff↓, eff↓,
EPR↑, Dose?,
Showing Research Papers: 1 to 4 of 4
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
ROS↑, 1,
Cell Death(tgid=5) ⓘ
Apoptosis↑, 1, Bcl-2↑, 1, Bcl-xL↓, 1, Casp3↑, 1, Casp8↑, 1, Casp9↑, 1, IAP1↓, 1, JNK↑, 1, p38↑, 1, survivin↓, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
cSrc↓, 1,
DNA Damage & Repair(tgid=10) ⓘ
cl‑PARP↑, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
ERK↑, 1, p‑STAT3↓, 1,
Migration(tgid=13) ⓘ
AXL↓, 1, MMP9↓, 1, TumCP↓, 2, TumMeta↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
EPR↑, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX2↓, 1, JAK2↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
Dose?, 4, eff↓, 4, eff↑, 1,
Total Targets: 26
Pathway results for Effect on Normal Cells:
Functional Outcomes(tgid=23) ⓘ
toxicity↑, 1,
Total Targets: 1
Scientific Paper Hit Count for: Dose, Dosage
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:4 Cells:% prod#:% Target#:1114 State#:% Dir#:0
wNotes=0 sortOrder:rid,rpid
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