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| Type: |
| Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M). Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division). |
| Breast Cancer |
| 1000- | AG, | 5-FU, | Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation |
| - | vitro+vivo, | BC, | 4T1 |
| 374- | AgNPs, | Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| 4400- | AgNPs, | Rad, | Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Nor, | MCF10 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | BT549 | - | in-vivo, | BC, | MDA-MB-231 |
| 4413- | AgNPs, | Anzaroot, | Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells |
| - | in-vitro, | BC, | MCF-7 |
| 4407- | AgNPs, | Green Synthesis and Characterization of Silver Nanoparticles from Eclipta alba and Its Activity Against Triple-Negative Breast Cancer Cell Line (MDA-MB-231) |
| - | in-vitro, | BC, | MDA-MB-231 |
| 4593- | AgNPs, | Chit, | Chitosan-coated silver nanoparticles promoted antibacterial, antibiofilm, wound-healing of murine macrophages and antiproliferation of human breast cancer MCF 7 cells |
| - | in-vitro, | BC, | MCF-7 |
| 296- | ALA, | Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo |
| - | vitro+vivo, | neuroblastoma, | SK-N-SH | - | vitro+vivo, | BC, | SkBr3 |
| 297- | ALA, | Insights on the Use of α-Lipoic Acid for Therapeutic Purposes |
| - | Review, | BC, | SkBr3 | - | Review, | neuroblastoma, | SK-N-SH | - | Review, | AD, | NA |
| 258- | ALA, | Effects of α-lipoic acid on cell proliferation and apoptosis in MDA-MB-231 human breast cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 1348- | And, | Andrographolide Inhibits ER-Positive Breast Cancer Growth and Enhances Fulvestrant Efficacy via ROS-FOXM1-ER-α Axis |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | T47D | - | in-vivo, | NA, | NA |
| - | in-vitro, | BC, | BT474 |
| 179- | Api, | Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells |
| - | in-vitro, | BC, | SkBr3 |
| 5173- | Ash, | 2DG, | Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | BC, | T47D |
| 5451- | ATV, | In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | GBM, | U87MG | - | in-vitro, | GBM, | A172 |
| 5543- | BBM, | Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo |
| - | in-vivo, | Lung, | B16-F10 | - | vitro+vivo, | Lung, | A549 | - | in-vitro, | BC, | MDA-MB-231 |
| 762- | Bor, | Mechanism of boric acid cytotoxicity in breast cancer cell lines |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | ZR-75-1 |
| 1447- | Bos, | Boswellia carterii n-hexane extract suppresses breast cancer growth via induction of ferroptosis by downregulated GPX4 and upregulated transferrin |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MCF-7 | - | in-vivo, | BC, | 4T1 | - | in-vitro, | Nor, | MCF10 |
| 6559- | BSB, | Modulatory effect of α-Bisabolol on induced apoptosis via mitochondrial and NF-κB/Akt/PI3K Signaling pathways in MCF-7 breast cancer cells |
| - | in-vitro, | BC, | MCF-7 |
| 2050- | Buty, | The Role of Sodium Phenylbutyrate in Modifying the Methylome of Breast Cancer Cells |
| - | in-vitro, | BC, | MCF-7 |
| 1230- | CA, | Caff, | Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 | - | Human, | NA, | NA |
| 5764- | CAPE, | Caffeic Acid Phenethyl Ester (CAPE), Derived from a Honeybee Product Propolis, Exhibits a Diversity of Anti-tumor Effects in Preclinical Models of Human Breast Cancer |
| - | vitro+vivo, | BC, | MCF-7 | - | NA, | BC, | MDA-MB-231 |
| 5895- | CAR, | Carvacrol as a Therapeutic Candidate in Breast Cancer: Insights into Subtype-Specific Cellular Modulation |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 |
| 6642- | Cen, | Asiaticoside inhibits breast cancer progression and tumor angiogenesis via YAP1/VEGFA signal pathway |
| - | vitro+vivo, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 |
| 6641- | Cen, | Asiaticoside Increases Caspase-9 Activity in MCF-7 Cells and Inhibits TNF-α and IL-6 Expression in Nude Mouse Xenografts via the NF-κB Pathway |
| - | in-vitro, | BC, | MCF-7 |
| 6030- | CGA, | Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway |
| - | vitro+vivo, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-453 | - | in-vitro, | Nor, | MCF10 |
| 2798- | CHr, | Chrysin: a histone deacetylase 8 inhibitor with anticancer activity and a suitable candidate for the standardization of Chinese propolis |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| 952- | Cin, | Cinnamon Extract Reduces VEGF Expression Via Suppressing HIF-1α Gene Expression and Inhibits Tumor Growth in Mice |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | GBM, | U251 | - | in-vivo, | Ovarian, | SKOV3 |
| 4772- | CoQ10, | The anti-tumor activities of coenzyme Q0 through ROS-mediated autophagic cell death in human triple-negative breast cells |
| - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | BC, | MDA-MB-231 |
| 6305- | Cro, | Bridging Preclinical and Clinical Evidence on Crocin in Breast Cancer |
| - | Review, | BC, | NA |
| 6186- | Cuc, | Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity |
| - | vitro+vivo, | Lung, | A549 | - | in-vitro, | BC, | MDA-MB-453 |
| 6191- | Cuc, | Growth inhibitory effect of Cucurbitacin E on breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 6203- | Cuc, | immuno, | Isocucurbitacin B targets STAT3 to induce ferroptosis and promote anti-PD1 immunotherapy responses in breast cancer |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | BT549 | - | in-vivo, | BC, | 4T1 |
| 1867- | DCA, | Chemo, | Sensitization of breast cancer cells to paclitaxel by dichloroacetate through inhibiting autophagy |
| - | in-vivo, | BC, | NA | - | in-vitro, | BC, | NA |
| 1865- | DCA, | Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo |
| - | in-vivo, | BC, | NA | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | T47D |
| 1443- | Deg, | Deguelin Action Involves c-Met and EGFR Signaling Pathways in Triple Negative Breast Cancer Cells |
| - | vitro+vivo, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-435 | - | in-vitro, | BC, | BT549 |
| 1446- | Deg, | Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells |
| - | in-vitro, | BC, | 4T1 |
| 1183- | DHA, | Docosahexaenoic acid inhibited the Wnt/β-catenin pathway and suppressed breast cancer cells in vitro and in vivo |
| - | in-vitro, | BC, | 4T1 | - | in-vitro, | BC, | MCF-7 | - | in-vivo, | BC, | NA |
| 1857- | dietFMD, | Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy |
| - | in-vitro, | BC, | 4T1 | - | in-vivo, | NA, | NA |
| 1859- | dietFMD, | Chemo, | Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity |
| - | in-vitro, | BC, | 4T1 | - | in-vivo, | Melanoma, | B16-BL6 |
| 1860- | dietFMD, | Chemo, | Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape |
| - | in-vitro, | BC, | SUM159 | - | in-vitro, | BC, | 4T1 |
| 6276- | DL, | Tam, | Combination of tamoxifen and D-limonene enhances therapeutic efficacy in breast cancer cells |
| - | in-vitro, | BC, | MCF-7 |
| 6328- | DRE, | Hydroalcoholic extract of Taraxacum officinale induces apoptosis and autophagy in 4T1 breast cancer cells |
| - | in-vitro, | BC, | 4T1 |
| 6327- | DRE, | Effect of Methanolic Extract of Dandelion Roots on Cancer Cell Lines and AMP-Activated Protein Kinase Pathway |
| - | in-vitro, | Liver, | HepG2 | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Nor, | Hs27 |
| 6384- | Eug, | Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-453 |
| 6339- | Eug, | Induction of apoptosis by eugenol in human breast cancer cells |
| - | in-vitro, | BC, | NA |
| 987- | GA, | Targeting Aerobic Glycolysis: Gallic Acid as Promising Anticancer Drug |
| - | in-vitro, | GBM, | AMGM | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | BC, | MCF-7 |
| 1969- | GamB, | Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| 799- | GAR, | Apoptosis-inducing effect of garcinol is mediated by NF-kappaB signaling in breast cancer cells |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | NMSC, | MCF10 |
| 28- | GEN, | Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway |
| - | in-vivo, | BC, | MCF-7 |
| 855- | Gra, | Antiproliferative activity of ionic liquid-graviola fruit extract against human breast cancer (MCF-7) cell lines using flow cytometry techniques |
| - | in-vitro, | BC, | MCF-7 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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