BioAv Cancer Research Results
BioAv, bioavailability: Click to Expand ⟱
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| Type: measurement |
Bioavailability (usually in %) absorbed by the body.
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BC, Breast Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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in-vivo, |
Lung, |
B16-F10 |
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vitro+vivo, |
Lung, |
A549 |
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in-vitro, |
BC, |
MDA-MB-231 |
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BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,
BioAv↓, BioAv↑, selectivity↑, eff↑, angioG↓, *antiOx↑, *Inflam↓, MMP↓, Bcl-2↓, BAX↑, Casp9↑, Casp3↑, GRP78/BiP?, ER Stress↑, PERK↑, CHOP/DDIT3↑, ChemoSen↑, SESN2↑, ROS↑, MOMP↓, MAPK↑, Cyt‑c↑, AIF↑, STAT3↓, FAK↓, TIMP2↑, TumCMig↓, TumCI↓, Sp1/3/4↓, TumCCA↑, DNAdam↑,
*other↝, *BioAv↓, eff↑, toxicity↓, eff↑, TumCD↑, Half-Life↑, selectivity↑, EPR↑, ROS↑, Apoptosis↑, eff↑,
CSCs↓, *BioAv↓,
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in-vitro, |
Cerv, |
HeLa |
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in-vitro, |
Liver, |
HepG2 |
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in-vitro, |
BC, |
MCF7 |
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in-vitro, |
Lung, |
A549 |
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in-vitro, |
Nor, |
HUVECs |
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eff↑, Dose∅, *BioAv↑, selectivity↑, TumCP↓, Casp↑, PTEN↑, TSC1↑, mTOR⇅, Akt↓, PDK1↓, E6↓, E7↓, DNAdam↑, ROS↑, *BioAv↓, *BioEnh↑, *Half-Life∅,
TumCCA↑, CDK4↓, RadioS↑, TumCG↓, *radioP↑, *cardioP↑, *antiOx↑, *ROS↓, Dose↑, selectivity↑, BioAv↓,
UGDH↓, UGDH↓, TumCP↓, Dose↑, *BioAv↓, eff?,
*ROS↓, *Inflam↓, CSCs↓, ChemoSen↑, BioAv↑, ROS↑, MMP↓, mtDam↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, Casp3↑, Casp9↑, Bcl-2↓, Bcl-xL↓, BAX↑, p‑STAT3↓, AMPK↑, miR-34a↑, EMT↓, HH↓, Shh↓, Gli1↓, PTCH1↓, NF-kB↓, TNF-α↓, IL6↓, Glycolysis↓, GlucoseCon↓, BioAv↓, BioAv↓, Half-Life↝,
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in-vitro, |
BC, |
4T1 |
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in-vivo, |
NA, |
NA |
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BioAv↓, BioAv↑, eff↑, tumCV↓, e-H2O2↓, i-H2O2∅,
Showing Research Papers: 1 to 9 of 9
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 9
Pathway results for Effect on Cancer / Diseased Cells:
NA, unassigned(tgid=0) ⓘ
UGDH↓, 2,
Redox & Oxidative Stress(tgid=1) ⓘ
e-H2O2↓, 1, i-H2O2∅, 1, ROS↑, 4,
Mitochondria & Bioenergetics(tgid=3) ⓘ
AIF↑, 1, MMP↓, 2, mtDam↑, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
AMPK↑, 1, GlucoseCon↓, 1, Glycolysis↓, 1, PDK1↓, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 1, Apoptosis↑, 2, BAX↑, 2, Bcl-2↓, 3, Bcl-xL↓, 1, Casp↑, 1, Casp3↑, 2, Casp9↑, 2, Cyt‑c↑, 1, MAPK↑, 1, MOMP↓, 1, TumCD↑, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
Sp1/3/4↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
tumCV↓, 1,
Protein Folding & ER Stress(tgid=8) ⓘ
CHOP/DDIT3↑, 1, ER Stress↑, 1, GRP78/BiP?, 1, PERK↑, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
SESN2↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↑, 2,
Cell Cycle & Senescence(tgid=11) ⓘ
CDK4↓, 2, cycD1/CCND1↓, 1, TumCCA↑, 4,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
CSCs↓, 2, EMT↓, 1, Gli1↓, 1, HH↓, 1, miR-34a↑, 1, mTOR⇅, 1, PTCH1↓, 1, PTEN↑, 1, Shh↓, 1, STAT3↓, 1, p‑STAT3↓, 1, TumCG↓, 2,
Migration(tgid=13) ⓘ
FAK↓, 1, MMP2↓, 1, MMP9↓, 1, TIMP2↑, 1, TSC1↑, 1, TumCI↓, 1, TumCMig↓, 1, TumCP↓, 3, TumMeta↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
angioG↓, 1, EPR↑, 2, VEGF↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
IL6↓, 1, NF-kB↓, 1, TNF-α↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↓, 6, BioAv↑, 3, ChemoSen↑, 2, Dose↑, 2, Dose∅, 1, eff?, 1, eff↑, 8, Half-Life↓, 1, Half-Life↑, 1, Half-Life↝, 1, RadioS↑, 1, selectivity↑, 4,
Clinical Biomarkers(tgid=22) ⓘ
E6↓, 1, E7↓, 1, IL6↓, 1,
Functional Outcomes(tgid=23) ⓘ
toxicity↓, 1,
Total Targets: 77
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 2, ROS↓, 2,
Transcription & Epigenetics(tgid=7) ⓘ
other↝, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
Inflam↓, 2,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↓, 4, BioAv↑, 1, BioEnh↑, 1, Half-Life∅, 1,
Functional Outcomes(tgid=23) ⓘ
cardioP↑, 1, radioP↑, 1,
Total Targets: 10
Scientific Paper Hit Count for: BioAv, bioavailability
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:4 Cells:% prod#:% Target#:792 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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