SCD1 Cancer Research Results

SCD1, Stearoyl-CoA Desaturase 1: Click to Expand ⟱
Source:
Type:
Stearoyl-CoA Desaturase 1 (SCD1) is an enzyme that plays a crucial role in the regulation of fatty acid metabolism, particularly in the synthesis of monounsaturated fatty acids.
Lipid synthesis gene.

SCD1 is overexpressed and is associated with poor prognosis and reduced overall survival in breast, lung, and colon cancers.
-SCD1 expression is also associated with increased risk of metastasis and recurrence in various types of cancer.
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
6342- DRE,    Mechanistic Study on the Inhibitory Effect of Dandelion Extract on Breast Cancer Cell Proliferation and Its Induction of Apoptosis
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
eff↑, selectivity↑, Apoptosis↑, TumCCA↑, PI3K↓, Akt↓, JAK1↓, STAT↓, PPARγ↑, TumCP↓, SIRT6↓, SCD1↓, STAT3↓, Casp8↓, STAT6↓, PAK1↓, FABP4↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

FABP4↓, 1,   PPARγ↑, 1,   SCD1↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 1,   Casp8↓, 1,  

DNA Damage & Repair ⓘ

SIRT6↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

PI3K↓, 1,   STAT↓, 1,   STAT3↓, 1,   STAT6↓, 1,  

Migration ⓘ

PAK1↓, 1,   TumCP↓, 1,  

Immune & Inflammatory Signaling ⓘ

JAK1↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,   selectivity↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SCD1, Stearoyl-CoA Desaturase 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:958  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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