BBB Cancer Research Results

BBB, Blood-Brain Barrier Permeability: Click to Expand ⟱
Source:
Type:
Blood-Brain Barrier(BBB) is a term often used regarding if a product has the ability to cross the BBB.


neuroblastoma, Neuroblastoma: Click to Expand ⟱
Neuroblastoma is a type of cancer that develops in immature nerve tissue, usually affecting kids under age 5.

Scientific Papers found: Click to Expand⟱
6689- DFC,    Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase
- in-vitro, neuroblastoma, SH-SY5Y
Apoptosis↑, mtDam↑, ROS↑, SOD2↓, MMP↓, Cyt‑c↑, Dose↝, BBB↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

ROS↑, 1,   SOD2↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↓, 1,   mtDam↑, 1,  

Cell Death(tgid=5)

Apoptosis↑, 1,   Cyt‑c↑, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,  

Drug Metabolism & Resistance(tgid=21)

Dose↝, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BBB, Blood-Brain Barrier Permeability
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:40  Cells:%  prod#:%  Target#:1123  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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