DNAdam Cancer Research Results

DNAdam, DNA damage: Click to Expand ⟱
Source: HalifaxProj(prevent)
Type:
DNA damage plays a crucial role in the development of cancer. The integrity of DNA is essential for the proper functioning of cells, and when DNA is damaged, it can lead to mutations that may contribute to cancer progression.


Testi, Testicular Teratoma: Click to Expand ⟱
Testicular teratoma is most common between the ages of 20 to 30, though it can occur at any age.


Scientific Papers found: Click to Expand⟱
384- AgNPs,    Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy
- in-vitro, Testi, F9
LDH↓, ROS↑, mtDam↑, DNAdam↑, P53↑, P21↑, BAX↑, Casp3↑, Bcl-2↓, Casp9↑, Nanog↓, OCT4↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↑, 1,  

Mitochondria & Bioenergetics

mtDam↑, 1,  

Core Metabolism/Glycolysis

LDH↓, 1,  

Cell Death

BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Casp9↑, 1,  

DNA Damage & Repair

DNAdam↑, 1,   P53↑, 1,  

Cell Cycle & Senescence

P21↑, 1,  

Proliferation, Differentiation & Cell State

Nanog↓, 1,   OCT4↓, 1,  

Clinical Biomarkers

LDH↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: DNAdam, DNA damage
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:44  Cells:%  prod#:%  Target#:82  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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