Cancer Database Query Results

CKD, Chronic Kidney Disease: Click to Expand ⟱
Chronic Kidney Disease
Scientific Papers found: Click to Expand⟱
2870- HNK,    Honokiol attenuates oxidative stress and vascular calcification via the upregulation of heme oxygenase-1 in chronic kidney disease
- in-vitro, CKD, NA
*HO-1↑, *ROS↓,
5619- NaHCO3,    Safety and efficacy of sodium bicarbonate for treating metabolic acidosis in chronic kidney disease: A systematic review and meta-analysis
- Review, CKD, NA
*eff↑, toxicity↓, GFR↑, toxicity↝,
2363- SK,    Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis
- in-vivo, CKD, NA
PKM2↓, lactateProd↓, TGF-β↓,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

lactateProd↓, 1,   PKM2↓, 1,  

Migration ⓘ

TGF-β↓, 1,  

Functional Outcomes ⓘ

GFR↑, 1,   toxicity↓, 1,   toxicity↝, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

HO-1↑, 1,   ROS↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  
Total Targets: 3

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:48  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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