antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
6273- DL,    D-Limonene Exhibits Antiproliferative Activity Against Human Colorectal Adenocarcinoma (Caco-2) Cells via Regulation of Inflammatory and Apoptotic Pathways
- in-vitro, Colon, Caco-2 - in-vitro, Nor, HEK293 - in-vitro, Colon, HCT116
ROS↑, antiOx↓, GSH↓, Casp3↑, BAX↑, P53↑, LDH↑, TNF-α↑, IL1β↑, MMP2↓, MMP9↓, Ki-67↓, Bcl-2↓, selectivity↑,
6574- EU,    Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
- in-vivo, Nor, NA
*cognitive↑, *antiOx↓, *MDA↓, *CRP↓, *neuroP↑, *Inflam↓,
6376- Eug,    Preparation, characterization, oral bioavailability, and pharmacodynamic study of eugenol-porous silica solidified powder
- NA, Nor, NA
*Inflam↓, *antiOx↓, *Dose↝, *eff↑,
2431- QC,    The Protective Effect of Quercetin against the Cytotoxicity Induced by Fumonisin B1 in Sertoli Cells
- in-vitro, Nor, TM4
*Apoptosis↓, *ROS↓, *antiOx↓, *MMP↑, *GPI↑, *HK2↑, *ALDOA↑, *PKM1↑, *LDHA↑, *PFKL↑,
3361- QC,    Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats
- in-vivo, Nor, NA - in-vitro, NA, NA
*BG↓, *ROS↓, *SOD↑, *MDA↓, *ER Stress↓, *iNOS↓, *CHOP↓, *GRP78/BiP↓, *antiOx↓, *Inflam↓, *JAK2↑, *STAT3?,
1937- TQ,    Migration and Proliferation Effects of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) and Thymoquinone (TQ) on In Vitro Wound Healing Models
- NA, Nor, 3T3
*ROS↓, *antiOx↓, *BioAv↓, *BioAv↑, *NO↑, *SOD↑, *GPx↑, *Catalase↑,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   GSH↓, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis ⓘ

LDH↑, 1,  

Cell Death ⓘ

BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Migration ⓘ

Ki-67↓, 1,   MMP2↓, 1,   MMP9↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↑, 1,   TNF-α↑, 1,  

Drug Metabolism & Resistance ⓘ

selectivity↑, 1,  

Clinical Biomarkers ⓘ

Ki-67↓, 1,   LDH↑, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 5,   Catalase↑, 1,   GPx↑, 1,   MDA↓, 2,   ROS↓, 3,   SOD↑, 2,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALDOA↑, 1,   GPI↑, 1,   HK2↑, 1,   LDHA↑, 1,   PFKL↑, 1,   PKM1↑, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   iNOS↓, 1,  

Protein Folding & ER Stress ⓘ

CHOP↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

STAT3?, 1,  

Angiogenesis & Vasculature ⓘ

NO↑, 1,  

Immune & Inflammatory Signaling ⓘ

CRP↓, 1,   Inflam↓, 3,   JAK2↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 1,   Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers ⓘ

BG↓, 1,   CRP↓, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,   neuroP↑, 1,  
Total Targets: 31

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
2 Quercetin
1 D-limonene
1 Eurycomanone
1 Eugenol
1 Thymoquinone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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