Pain Cancer Research Results

Pain, Pain: Click to Expand ⟱
Source:
Type:
Pain


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy

Scientific Papers found: Click to Expand⟱
6510- BCP,  CBD,    Cannabidiol and Beta-Caryophyllene Combination Attenuates Diabetic Neuropathy by Inhibiting NLRP3 Inflammasome/NFκB through the AMPK/sirT3/Nrf2 Axis
- in-vivo, Nor, NA
*MMP↓, *ROS↑, *BloodF↑, *Pain↓, *antiOx↑, *Inflam↓, *AMPK↑, *SIRT3↑, *NRF2↑, *PINK1↑, *PARK2↑, *LC3B↑, *Beclin-1↑, *TFAM↑, *NLRP3↓, *NF-kB↓, *COX2↓, *p62↓, *NP/CIPN↓,
6508- BCP,    The CB2 Agonist β-Caryophyllene in Male and Female Rats Exposed to a Model of Persistent Inflammatory Pain
- in-vivo, Nor, NA
*Pain↓,
5661- BNL,    A clinical and mechanistic study of topical borneol‐induced analgesia
- Trial, Nor, NA
*Pain↓,
5842- CAP,    Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses
- Review, Nor, NA - Review, Diabetic, NA
*Pain↓, *TRPV1↑, AMPK↑, ROS↑, TumCP↑, Apoptosis↑, TumCCA↑, Casp3↑, BAX↑, Bak↑, cl‑PARP↑, Bcl-2↓, RNS↑, *glucose↓, *Insulin↑, *BP↓, *AntiAg↑, ER Stress↑, Hif1a↓, chemoPv↑,
5855- CAP,    Unravelling the Mystery of Capsaicin: A Tool to Understand and Treat Pain
- in-vivo, Nor, NA
NP/CIPN↓, BioAv↑, Half-Life↑, TRPV1↑, Pain↓, TRPV1↑,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2↓, *Dose↝,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
6411- EGCG,    Pharmacological and Genetic Approaches to Downregulate FIS1 Mitigate Neuropathic Pain
- in-vivo, Nor, NA
*FIS1↓, *Pain↓, *ROS↓,
2871- HNK,    Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling
- in-vivo, Nor, NA
*TNF-α↓, *IL1β↓, *IL6↓, *VEGF↓, *NRF2↑, *SOD2↑, *HO-1↑, *Inflam↓, *Pain↓, *NO↓, toxicity↓,
1272- LA,    Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- Trial, Nor, NA
*Pain↓, *other↑,
6541- MeSal,    Toxicology Answer: Oil of Wintergreen
- Review, Nor, NA
*Inflam↓, *Pain↓, *BioAv↝, *BloodF↑, *toxicity↑,

Showing Research Papers: 1 to 11 of 11

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 11

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

RNS↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics

MMP↓, 1,  

Core Metabolism/Glycolysis

AMPK↑, 1,  

Cell Death

Apoptosis↑, 1,   Bak↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   TRPV1↑, 2,  

Protein Folding & ER Stress

ER Stress↑, 1,  

DNA Damage & Repair

cl‑PARP↑, 1,  

Cell Cycle & Senescence

TumCCA↑, 1,  

Migration

TumCP↑, 1,  

Angiogenesis & Vasculature

Hif1a↓, 1,  

Immune & Inflammatory Signaling

PGE2↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 1,   BioAv↝, 1,   Half-Life↑, 1,  

Functional Outcomes

chemoPv↑, 1,   NP/CIPN↓, 1,   Pain↓, 1,   toxicity↓, 1,  
Total Targets: 23

Pathway results for Effect on Normal Cells:


NA, unassigned

FIS1↓, 1,   TFAM↑, 1,  

Redox & Oxidative Stress

antiOx↑, 3,   Catalase↑, 1,   GPx↑, 1,   GSR↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↑, 3,   PARK2↑, 1,   ROS↓, 1,   ROS↑, 1,   SIRT3↑, 1,   SOD↑, 1,   SOD2↑, 1,  

Mitochondria & Bioenergetics

ATP↑, 1,   Insulin↑, 1,   MMP↓, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis

AMPK↑, 1,   glucose↓, 1,  

Cell Death

TRPV1↑, 1,  

Kinase & Signal Transduction

TRPV3↑, 1,  

Transcription & Epigenetics

other↑, 2,   other↝, 1,  

Autophagy & Lysosomes

Beclin-1↑, 1,   LC3B↑, 1,   p62↓, 1,  

Migration

5LO↓, 1,   AntiAg↑, 3,   Ca+2↑, 1,  

Angiogenesis & Vasculature

NO↓, 1,   VEGF↓, 1,  

Barriers & Transport

GastroP↑, 1,  

Immune & Inflammatory Signaling

COX2↓, 3,   CRP↓, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 5,   NF-kB↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission

AChE↓, 1,   BChE↓, 1,  

Protein Aggregation

NLRP3↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 1,   BioAv↝, 1,   Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers

BloodF↑, 2,   BP↓, 1,   CRP↓, 1,   IL6↓, 1,  

Functional Outcomes

AntiDiabetic↑, 1,   cardioP↑, 2,   chemoPv↑, 1,   cognitive↑, 1,   hepatoP↑, 2,   neuroP↑, 2,   NP/CIPN↓, 1,   Obesity↓, 1,   OS↑, 1,   Pain↓, 10,   RenoP↑, 1,   toxicity↓, 2,   toxicity↑, 1,  

Infection & Microbiome

Bacteria↓, 1,   Diar↓, 1,  
Total Targets: 69

Scientific Paper Hit Count for: Pain, Pain
2 Beta-Caryophyllene
2 Capsaicin
2 Carvacrol
1 Cannabidiol
1 borneol
1 EGCG (Epigallocatechin Gallate)
1 Honokiol
1 Lactobacillus
1 Methyl salicylate / Sweet Birch oil
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:576  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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