BChE Cancer Research Results

BChE, butyrylcholinesterase: Click to Expand ⟱
Source:
Type:
BChE is an enzyme that hydrolyzes choline-based esters. In the brain, it works alongside acetylcholinesterase (AChE) to regulate levels of the neurotransmitter acetylcholine. Since cholinergic deficits are a hallmark of AD, both enzymes have been studied in relation to AD pathology.
- In some AD patients, BChE activity increases relative to AChE.
- Aβ neurotoxicity is amplified when BChE is added to Aβ in tissue culture
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
6553- BSB,    Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms
- Review, Nor, NA
*ROS↓, *Inflam↓, *Inf↓, *neuroP↑, *RNS↓, *MDA↓, *GSH↑, *MPO↓, *SOD↑, *Catalase↑, *Bcl-2↑, *BAX↓, *P53↓, *APAF1↓, *Casp3↓, *Casp9↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2↓, *ERK↓, *JNK↓, *NF-kB↓, *p38↓, *cognitive↑, *BChE↓,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Immune & Inflammatory Signaling ⓘ

PGE2↓, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   Catalase↑, 1,   GSH↑, 1,   MDA↓, 1,   MPO↓, 1,   NRF2↑, 1,   RNS↓, 1,   ROS↓, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↑, 1,  

Cell Death ⓘ

APAF1↓, 1,   BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 1,   Casp9↓, 1,   iNOS↓, 1,   JNK↓, 1,   p38↓, 1,  

Kinase & Signal Transduction ⓘ

TRPV3↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

DNA Damage & Repair ⓘ

P53↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,  

Migration ⓘ

5LO↓, 1,   AntiAg↑, 1,   Ca+2↑, 1,  

Barriers & Transport ⓘ

GastroP↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 2,   CRP↓, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 2,   NF-kB↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   BChE↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   eff↑, 1,  

Clinical Biomarkers ⓘ

CRP↓, 1,   IL6↓, 1,  

Functional Outcomes ⓘ

cardioP↑, 1,   chemoPv↑, 1,   cognitive↑, 2,   hepatoP↑, 1,   neuroP↑, 2,   Pain↓, 1,   toxicity↓, 1,  

Infection & Microbiome ⓘ

Diar↓, 1,   Inf↓, 1,  
Total Targets: 48

Scientific Paper Hit Count for: BChE, butyrylcholinesterase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:606  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page