NGF Cancer Research Results

NGF, Nerve Growth Factor: Click to Expand ⟱
Source:
Type:
Nerve Growth Factor (NGF) plays a crucial role in the development, maintenance, and survival of certain neurons. Its connection to Alzheimer’s disease (AD) has been well-studied, particularly because of its importance in cholinergic neurons of the basal forebrain, which are notably affected in AD.
-Loss of NGF signaling contributes to cholinergic deficits, a hallmark of AD pathology
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
7230- EGb 761,    Ginkgo biloba extract (EGb 761) promotes peripheral nerve regeneration and neovascularization after acellular nerve allografts in a rat model
- in-vivo, Nor, NA
*Dose↝, *NGF↑, *angioG↑, *VEGF↑, *SOX18↑, *CD133↑, *IL6↑,
7517- Poly,    Modulation of neurotrophic signaling pathways by polyphenols
- Review, Nor, NA
*NRF2↑, *HO-1↑, *NGF↑, *BDNF↑, *neuroP↑, p‑CREB↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis(tgid=4) ⓘ

p‑CREB↑, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

HO-1↑, 1,   NRF2↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   SOX18↑, 1,   VEGF↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL6↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↑, 1,   NGF↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↑, 1,  

Functional Outcomes(tgid=23) ⓘ

neuroP↑, 1,  
Total Targets: 12

Scientific Paper Hit Count for: NGF, Nerve Growth Factor
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1360  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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