diuretic Cancer Research Results

diuretic, diuretic: Click to Expand ⟱
Source:
Type:

diuretic is a substance that makes the body produce and excrete more urine.

| Use                                   | Why diuretics help                                     |
| ------------------------------------- | ------------------------------------------------------ |
| High blood pressure                   | Lower fluid volume, reducing pressure in blood vessels |
| Edema / swelling                      | Remove excess fluid from tissues                       |
| Heart failure                         | Reduce fluid overload                                  |
| Kidney or liver-related fluid buildup | Help manage retained fluid                             |


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
6820- EMD,    The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update
- Review, Nor, NA - Review, Arthritis, NA - Review, AD, NA
*diuretic↑, *Bacteria↓, *Inflam↓, AntiCan↑, TumCP↓, TumCI↓, angioG↓, *toxicity↓, IFN-γ↑, IL12↑, ROS↑, TNF-α↓, TNF-α↓, TGF-β↓, MAPK↓, PKCδ↓, NF-kB↓, HER2/EBBR2↓, VEGF↓, DNAdam↑, Necroptosis↑, Glycolysis↓, GLUT1↓, PI3K↓, Akt↓, Casp9↑, Casp3↑, BAX↑, Bcl-2↓, eff↑, MMP2↓, MMP9↓, eff↑, ChemoSen↑, P-gp↓, SREBP2↓, eff↑, *other↝, *COX2↓, *Hif1a↓, *HDAC↓, *tau↓, *PKCδ↑, *ROS↓, *Inflam↓, AntiAg?,
6836- EMD,    Emodin and the Anthraquinone Scaffold: Therapeutic Promise and Strategies to Overcome Translational Barriers
- Review, Nor, NA
*antiOx↑, *neuroP↑, *Inflam↓, *hepatoP↑, AntiTum↑, *Bacteria↓, *diuretic↑, *AntiDiabetic↑, *BioAv↝, *NF-kB↓, *AMPK↑, *JAK↓, *STAT3↓, *ROS↓, *lipid-P↓, ROS↑, TumCCA↑, CycB/CCNB1↓, BAX↑, Bcl-2↓, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp7↑, Apoptosis↑, P53↑,
7360- HibSad,    Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa
- Study, Nor, NA
*diuretic↑, *BP↓, *ACE↓,
7376- RS,    RENESE-R- polythiazide and reserpine tablet
- Review, Nor, NA
*BP↓, *BioAv↑, *Half-Life↑, *BBB↑, *diuretic↑, *toxicity↝,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Glycolysis↓, 1,   SREBP2↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 2,   Bcl-2↓, 2,   Casp3↑, 2,   Casp7↑, 1,   Casp9↑, 2,   Cyt‑c↑, 1,   MAPK↓, 1,   MOMP↑, 1,   Necroptosis↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CycB/CCNB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

PI3K↓, 1,  

Migration(tgid=13) ⓘ

AntiAg?, 1,   MMP2↓, 1,   MMP9↓, 1,   PKCδ↓, 1,   TGF-β↓, 1,   TumCI↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IFN-γ↑, 1,   IL12↑, 1,   NF-kB↓, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   eff↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

HER2/EBBR2↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,  
Total Targets: 40

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

ACE↓, 1,   diuretic↑, 4,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   lipid-P↓, 1,   ROS↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HDAC↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

PKCδ↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 1,   Inflam↓, 3,   JAK↓, 1,   NF-kB↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

tau↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   BioAv↝, 1,   Half-Life↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BP↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   toxicity↓, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 2,  
Total Targets: 27

Scientific Paper Hit Count for: diuretic, diuretic
2 Emodin
1 Hibiscus sabdariffa
1 Rauwolfia serpentina/Indian Snakeroot
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1480  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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