CD31 Cancer Research Results

CD31, platelet endothelial cell adhesion molecule-1 (PECAM-1): Click to Expand ⟱
Source:
Type: marker
CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a transmembrane receptor that plays a crucial role in various cellular processes, including cell adhesion, migration, and signaling.
High CD31 expression has been linked to poor prognosis and increased metastasis. (except Leukemia and brain cancers).
CD31 is a marker that is commonly used to identify microvessels in tissue sections.


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy

Scientific Papers found: Click to Expand⟱
6983- Form,    Formononetin enhances angiogenesis in diabetic wounds by inhibiting ferroptosis through suppression of mtROS-mediated xCT/GPX4 upregulation
- vitro+vivo, Nor, HUVECs - vitro+vivo, Diabetic, NA
*BloodF↑, *Ferroptosis↓, *eff↓, *mtDam↓, *xCT↑, *GPx4↑, *Wound Healing↑, *CD31↑, *mt-ROS↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

Ferroptosis↓, 1,   GPx4↑, 1,   mt-ROS↓, 1,   xCT↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

mtDam↓, 1,  

Cell Death(tgid=5)

Ferroptosis↓, 1,  

Migration(tgid=13)

CD31↑, 1,  

Drug Metabolism & Resistance(tgid=21)

eff↓, 1,  

Clinical Biomarkers(tgid=22)

BloodF↑, 1,  

Functional Outcomes(tgid=23)

Wound Healing↑, 1,  
Total Targets: 10

Scientific Paper Hit Count for: CD31, platelet endothelial cell adhesion molecule-1 (PECAM-1)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:295  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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