AntiTum Cancer Research Results

AntiTum, AntiTumor: Click to Expand ⟱
Source:
Type:
AntiTumor


Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
5424- ASTX,    Astaxanthin exerts an adjunctive anti-cancer effect through the modulation of gut microbiota and mucosal immunity
- in-vivo, Nor, NA
*GutMicro↑, AntiCan↑, eff↑, AntiTum↑, ChemoSen↑,
4818- ASTX,  MEL,    Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D - in-vitro, Nor, MCF10
TumCD↑, DNAdam↑, *antiOx↑, *AntiTum↑, Inflam↓, tumCV↓, Bcl-2↓, Apoptosis↓, selectivity↑, eff↑, Dose↓,
5365- AV,    Aloe Vera Polysaccharides as Therapeutic Agents: Benefits Versus Side Effects in Biomedical Applications
- Review, Nor, NA - Review, IBD, NA - Review, Diabetic, NA
*Wound Healing↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *AntiCan↑, *Inflam↓, *NF-kB↓, *COX2↓, *5LO↓, *IL1β↓, *IL6↓, *TNF-α↓, *IL10↑, *other↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *DNAdam↓, *GutMicro↑, *ZO-1↑, AntiTum↑, Casp3↑, Casp9↑, angioG↓, MMPs↓, VEGF↓, NK cell↑,
2022- BBR,  GoldNP,  Rad,    Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition
- in-vitro, Liver, SMMC-7721 cell - in-vitro, Nor, HL7702
*toxicity↓, radioP↑, BioAv↑, AntiTum↑, selectivity↑, eff↑, chemoP↑,
2724- BetA,    Down-regulation of NOX4 by betulinic acid protects against cerebral ischemia-reperfusion in mice
- in-vivo, Nor, NA - in-vivo, Stroke, NA
AntiTum↑, *Inflam↓, *ROS↓, *NOX4↓, *Apoptosis↓, neuroP↑,
5718- BF,    Bufalin inhibits CYP3A4 activity in vitro and in vivo
- in-vivo, Nor, NA
CYP3A4↓, Apoptosis↑, AntiTum↑,
2024- Bos,    Antiproliferative and cell cycle arrest potentials of 3-O-acetyl-11-keto-β-boswellic acid against MCF-7 cells in vitro
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10
MMP↓, Cyt‑c↑, ROS↑, Casp8↑, Casp9↑, AntiTum↑, selectivity↑, TumCCA↑,
2047- Buty,    Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells
- in-vitro, CRC, T24/HTB-9 - in-vitro, Nor, SV-HUC-1 - in-vitro, Bladder, 5637 - in-vivo, NA, NA
HDAC↓, AntiTum↑, TumCMig↓, AMPK↑, mTOR↑, TumAuto↑, ROS↑, miR-139-5p↑, BMI1↓, TumCI?, E-cadherin↑, N-cadherin↓, Vim↓, Snail↓, cl‑PARP↑, cl‑Casp3↑, BAX↑, Bcl-2↓, Bcl-xL↓, MMP↓, PINK1↑, PARK2↑, TumMeta↓, TumCG↓, LC3II↑, p62↓, eff↓,
5880- CAR,    In vitro and in vivo antitumor potential of carvacrol nanoemulsion against human lung adenocarcinoma A549 cells via mitochondrial mediated apoptosis
- vitro+vivo, Lung, A549 - in-vitro, Nor, BEAS-2B - in-vitro, Lung, PC9
Dose↝, mt-ROS↑, p‑JNK↑, BAX↑, Cyt‑c↑, Casp↑, AntiTum↑, ER Stress↑, LDH↑, selectivity↑, Apoptosis↑, DNAdam↑, IRE1↑, XBP-1↑, CHOP/DDIT3↓, p‑eIF2α↓, GRP78/BiP↓, Ca+2↑, MMP↓, Bcl-2↓, Casp3↑, Casp9↑, eff↓, TumW↓, Weight↑, eff↑, eff↑,
6010- CGA,    The Biological Activity Mechanism of Chlorogenic Acid and Its Applications in Food Industry: A Review
- Review, Nor, NA
*antiOx↑, *hepatoP↑, *RenoP↑, AntiTum↑, *glucose↝, *Inflam↓, *neuroP↑, *ROS↓, *Keap1↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *MDA↓, *p‑ERK↑, *GRP78/BiP↑, *CHOP/DDIT3↑, *GRP94↑, *Casp3↓, *Casp9↓, *HGF/c-Met↑, *TNF-α↓, *TLR4↓, *MAPK↓, *IL1β↓, *iNOS↓, TCA↓, Glycolysis↓, Bcl-2↓, BAX↑, MAPK↑, JNK↑, CSCs↓, Nanog↓, SOX2↓, CD44↓, OCT4↓, P53↑, P21↑, *SOD1↑, *AGEs↓, *GLUT2↑, *HDL↑, *Fas↓, *HMG-CoA↓, *NF-kB↓, *HO-1↓, *COX2↓, *TLR4↓, *BioAv↑, *BioAv↝, TumCP↓, TumCMig↓, TumCI↓,
6030- CGA,    Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway
- vitro+vivo, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453 - in-vitro, Nor, MCF10
NF-kB↓, AntiTum↑, tumCV↓, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, EMT↓, TumCG↓, OS↑, TumMeta↓, CD4+↑, CD8+↑, Imm↑,
6374- CPLE,    Antiviral & platelet-protective properties of Carica papaya in dengue
- Review, Nor, NA
*antiOx↑, *lipid-P↓, *AntiTum↑, Imm↑, CIT↓,
6300- Cro,    Interaction of saffron and its constituents with Nrf2 signaling pathway: A review
- Review, Nor, NA - Review, Arthritis, NA
*antiOx↑, *Inflam↓, *AntiTum↑, *hepatoP↑, *cardioP↑, *neuroP↑, *NRF2↑, *NF-kB↓, *iNOS↓, *COX2↓, *IL6↓, *IL10↓, *IL1β↓, *TNF-α↓, *HO-1↑, ROS↑, NQO1↑, NRF2↑, HO-1↑, NQO2↑, LDHA↓, ATP↓, *hepatoP↑, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑, *ROS↓, *cardioP↑, *ER Stress↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *Apoptosis↓, *miR-34a↓, *SIRT1↑, chemoP↑,
6825- EMD,    Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases
- Review, Nor, NA
*Inflam↓, *AntiTum↑, *Bacteria↓, *Imm↑, *glucose↓, *RenoP↑, *TLR4↓, *MyD88↓, *NLRP3↓, *NF-kB↓, *PI3K↓, *mTOR↓, *GSK‐3β↓, *Hif1a↓, *VEGF↓, *GutMicro↑, *Obesity↓, *AntiDiabetic↑, *AMPK↑, *PPARγ↑, *PPARγ↓, *toxicity↝, *hepatoP↑, *AST↓, *ALAT↓,
6836- EMD,    Emodin and the Anthraquinone Scaffold: Therapeutic Promise and Strategies to Overcome Translational Barriers
- Review, Nor, NA
*antiOx↑, *neuroP↑, *Inflam↓, *hepatoP↑, AntiTum↑, *Bacteria↓, *diuretic↑, *AntiDiabetic↑, *BioAv↝, *NF-kB↓, *AMPK↑, *JAK↓, *STAT3↓, *ROS↓, *lipid-P↓, ROS↑, TumCCA↑, CycB/CCNB1↓, BAX↑, Bcl-2↓, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp7↑, Apoptosis↑, P53↑,
6848- EVO,    Evodiamine: A Extremely Potential Drug Development Candidate of Alkaloids from Evodia rutaecarpa
- Review, Nor, NA
AntiTum↑, cardioP↑, Inflam↓, TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, BioAv↓, toxicity↑, NF-kB↓, MAPK↓, NOD1↓, p‑Akt↓, BAX↑, cl‑Casp3↑, γH2AX↑, cl‑PARP↑, ROS↑, BBB↑, neuroP↑, BioAv↑,
7018- Fuc,    Absorption Study of Mozuku Fucoidan in Japanese Volunteers
- Trial, Nor, NA
*Dose↝, *BioAv↝, *eff↝, *Inflam↓, *AntiThr↑, angioG↓, *AntiViral↑, *AntiTum↑, *antiOx↓, *BioAv↝,
7029- GA,    Gallic acid induces G1 phase arrest and apoptosis of triple-negative breast cancer cell MDA-MB-231 via p38 mitogen-activated protein kinase/p21/p27 axis
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, HS587T - in-vitro, Nor, MCF10
AntiTum↑, tumCV↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, cycE/CCNE↓, CDK2↓, P21↑, p27/CDKN1B↑, Casp9↑, Casp3↑, ROS↑, mtDam↑, i-Ca+2↑, *ROS↓, *Apoptosis↓, TumCG↓,
7028- GA,    Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases
- Review, Nor, NA
*toxicity↓, *Inflam↓, *NF-kB↓, AntiTum↑, Bacteria↓, *AntiDiabetic↑, *Obesity↓, *AntiBio↑, *Stroke↓, *NO↓, *PGE2↓, *IL6↓, *MAPK↓, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *ICAM-1↓, *TIMP1↓,
7204- GAs,    The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba
- Review, Nor, NA
AntiTum↑, SUMO↓, antiNeop↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *toxicity↑, *ROS↑, *toxicity↝,
7117- Ge-132,    Organogermanium suppresses cell death due to oxidative stress in normal human dermal fibroblasts
- in-vitro, Nor, NA
*IL6↓, *Apoptosis↓, *toxicity↓, Imm↑, IFN-γ↑, NK cell↑, AntiTum↑, Pain↓, *Wound Healing↑,
7126- Ge-132,    Immune activation of Bio-Germanium in a randomized, double-blind, placebo-controlled clinical trial with 130 human subjects: Therapeutic opportunities from new insights
- Trial, Nor, NA
AntiTum↑, AntiCan↑, *AntiAge↑, *AntiViral↑, *Inflam↓, *NK cell↑, *Imm↑, *TNF-α↑,
7135- GI,    Examination of the Pharmacokinetics of Active Ingredients of Ginger in Humans
- Trial, Nor, NA
*Dose↝, *Half-Life↝, *antiOx↑, *Inflam↓, *AntiTum↑, *Half-Life↓,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, eff↑,
4528- MAG,    Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
- Review, Nor, NA
*Inflam↑, *cardioP↑, *angioG↓, *antiOx↑, *neuroP↑, *Bacteria↓, AntiTum↑, TumCG↓, TumCMig↓, TumCI↓, Apoptosis↑, E-cadherin↑, NF-kB↓, TumCCA↑, cycD1/CCND1↓, PCNA↓, Ki-67↓, MMP2↓, MMP7↓, MMP9↓, TumCG↓, Casp3↑, NF-kB↓, Akt↓, mTOR↓, LDH↓, Ca+2↑, eff↑, *toxicity↓, *BioAv↝, *PGE2↓, *TLR2↓, *TLR4↓, *MAPK↓, *PPARγ↓,
3000- PL,    Biological and physical approaches on the role of piplartine (piperlongumine) in cancer
- in-vitro, Nor, HUVECs - in-vitro, Laryn, HEp2
Inflam↓, AntiTum↑, *α-tubulin↓, selectivity↑, HIF2a↓, MCP1/CCL2↓,
6459- TUR,    Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis
- in-vivo, Nor, NA - in-vivo, Colon, NA
*NO?, eff↑, eff↑, AntiTum↑, *Inflam↓,

Showing Research Papers: 1 to 27 of 27

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 27

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CIT↓, 1,   NOD1↓, 1,   SUMO↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

HO-1↑, 1,   NQO1↑, 1,   NRF2↑, 1,   PARK2↑, 1,   ROS↑, 6,   mt-ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   MMP↓, 3,   mtDam↑, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   CYP3A4↓, 1,   Glycolysis↓, 1,   LDH↓, 1,   LDH↑, 1,   LDHA↓, 1,   TCA↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 6,   BAX↑, 5,   Bcl-2↓, 5,   Bcl-xL↓, 1,   Casp↑, 1,   Casp3↑, 5,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 5,   Cyt‑c↑, 3,   JNK↑, 1,   p‑JNK↑, 1,   MAPK↓, 1,   MAPK↑, 1,   MOMP↑, 1,   p27/CDKN1B↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↑, 1,   GRP78/BiP↓, 1,   IRE1↑, 1,   NQO2↑, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↑, 2,   cl‑PARP↑, 2,   PCNA↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 2,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMI1↓, 1,   CD44↓, 1,   CSCs↓, 1,   EMT↓, 1,   HDAC↓, 1,   mTOR↓, 1,   mTOR↑, 1,   Nanog↓, 1,   OCT4↓, 1,   SOX2↓, 1,   TumCG↓, 5,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   i-Ca+2↑, 1,   E-cadherin↑, 2,   Ki-67↓, 1,   miR-139-5p↑, 1,   MMP2↓, 1,   MMP7↓, 1,   MMP9↓, 1,   MMPs↓, 1,   N-cadherin↓, 1,   Snail↓, 1,   TumCI?, 1,   TumCI↓, 3,   TumCMig↓, 4,   TumCP↓, 3,   TumMeta↓, 2,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   HIF2a↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   IFN-γ↑, 1,   Imm↑, 3,   Inflam↓, 3,   MCP1/CCL2↓, 1,   NF-kB↓, 4,   NK cell↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 2,   ChemoSen↑, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 2,   eff↓, 2,   eff↑, 9,   selectivity↑, 6,  

Clinical Biomarkers(tgid=22) ⓘ

Ki-67↓, 1,   LDH↓, 1,   LDH↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   antiNeop↑, 1,   AntiTum↑, 21,   cardioP↑, 1,   chemoP↑, 2,   neuroP↑, 2,   OS↑, 2,   Pain↓, 1,   QoL↑, 1,   radioP↑, 2,   toxicity↑, 1,   TumVol↓, 1,   TumW↓, 1,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   CD8+↑, 1,  
Total Targets: 131

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   diuretic↑, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 8,   Catalase↑, 3,   GPx↑, 3,   GSH↑, 1,   HDL↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Keap1↓, 1,   lipid-P↓, 3,   MDA↓, 1,   NOX4↓, 1,   NRF2↑, 3,   ROS↓, 6,   ROS↑, 1,   SOD↑, 3,   SOD1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   AMPK↑, 2,   glucose↓, 1,   glucose↝, 1,   GLUT2↑, 1,   HMG-CoA↓, 1,   PPARγ↓, 2,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 4,   Casp3↓, 1,   Casp9↓, 1,   Fas↓, 1,   HGF/c-Met↑, 1,   iNOS↓, 2,   MAPK↓, 3,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   other↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑ERK↑, 1,   GSK‐3β↓, 1,   miR-34a↓, 1,   mTOR↓, 1,   PI3K↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   TIMP1↓, 1,   ZO-1↑, 1,   α-tubulin↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   Hif1a↓, 1,   NO?, 1,   NO↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 3,   ICAM-1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL1β↓, 4,   IL6↓, 4,   Imm↑, 3,   Inflam↓, 12,   Inflam↑, 1,   JAK↓, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   NF-kB↓, 6,   NK cell↑, 1,   PGE2↓, 2,   TLR2↓, 1,   TLR4↓, 4,   TNF-α↓, 4,   TNF-α↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   BioAv↝, 5,   Dose↝, 2,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   GutMicro↑, 3,   IL6↓, 4,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   AntiDiabetic↑, 4,   AntiTum↑, 6,   cardioP↑, 3,   hepatoP↑, 5,   neuroP↑, 4,   Obesity↓, 2,   RenoP↑, 2,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 2,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 3,   Bacteria↓, 4,  
Total Targets: 106

Scientific Paper Hit Count for: AntiTum, AntiTumor
2 Astaxanthin
2 Radiotherapy/Radiation
2 Chlorogenic acid
2 Emodin
2 Gallic acid
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Melatonin
1 Aloe anthraquinones
1 Berberine
1 Gold NanoParticles
1 Betulinic acid
1 Bufalin/Huachansu
1 Boswellia (frankincense)
1 Butyrate
1 Carvacrol
1 Carica papaya leaf extract
1 Crocetin
1 Evodiamine
1 Fucoidan
1 Ginkgolic acids
1 Ginger/6-Shogaol/Gingerol
1 Hydrogen Gas
1 Vitamin C (Ascorbic Acid)
1 Magnolol
1 Piperlongumine
1 Turmerones
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:913  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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