cellSen Cancer Research Results

cellSen, cellular senescence: Click to Expand ⟱

Source:

Type:

Cellular senescence is a state in which cells cease to divide and grow, often in response to DNA damage or other forms of cellular stress.
On one hand, senescence can prevent cancer by:
-Halting the proliferation of damaged cells, thereby preventing the accumulation of mutations that can lead to cancer
-Activating immune responses that can eliminate senescent cells.
-Producing anti-tumor factors that can inhibit the growth of nearby cancer cells.

On the other hand, senescence can also promote cancer by:
-Creating a pro-tumorigenic microenvironment that can support the growth of nearby cancer cells
-Producing pro-inflammatory factors that can promote cancer progression
-Contributing to the development of a senescence-associated secretory phenotype (SASP), which can promote cancer cell growth and metastasis.

Nor, Normal Healthy: Click to Expand ⟱

Normal Healthy

Scientific Papers found: Click to Expand⟱

6896-

FIS,

Fisetin is a senotherapeutic that extends health and lifespan

in-vivo,

Nor,

mice

*AntiAge↑, *cellSen↑, *selectivity⇅,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Immune & Inflammatory Signaling(tgid=16) ⓘ

cellSen↑, 1,

Drug Metabolism & Resistance(tgid=21) ⓘ

selectivity⇅, 1,

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,
Total Targets: 3

Scientific Paper Hit Count for: cellSen, cellular senescence

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells