Half-Life Cancer Research Results

Half-Life, Half-Life: Click to Expand ⟱
Source:
Type:
For many drugs, the half-life is the time it takes for half of the drug’s active substance to be eliminated from the bloodstream.
In medicine, knowing a drug’s half-life helps in designing treatment regimens that reduce adverse effects.
Nor, Normal Healthy: Click to Expand ⟱
Normal Healthy
Scientific Papers found: Click to Expand⟱
6469- 1,8-Cin,    Pharmacokinetic Studies of the Fragrance Compound 1,8-Cineol in Humans during Inhalation
- Human, Nor, NA
*BioAv↑, *Half-Life↝,
5291- 5-HTP,    Kinetics of l-5-hydroxytryptophan in healthy subjects
- in-vivo, Nor, NA
*Half-Life↝, *BioAv↑,
5456- AF,    Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent
- Trial, Nor, NA
*Dose?, *Half-Life↝, *Dose↑, *toxicity↝, *Bacteria↓, *Dose↑,
5443- AG,    Pharmacokinetics and tolerance of toal astragalosides after intravenous infusion of astragalosides injection in healthy Chinese volunteers
- Human, Nor, NA
*Dose↝, Half-Life↝, *toxicity↓,
4600- AgNPs,    Effects of particle size and coating on toxicologic parameters, fecal elimination kinetics and tissue distribution of acutely ingested silver nanoparticles in a mouse model
- in-vivo, Nor, NA
*Half-Life↝, *toxicity↓, *Dose↑, *other↝, *eff↝, *BioAv↓,
5322- ALC,    Comparison of pharmacokinetics of L-carnitine, Acetyl-L-carnitine and Propionyl-Lcarnitine after single oral administration of L-carnitine in healthy volunteers
- Human, Nor, NA
*Half-Life↝,
2569- ART/DHA,    A semiphysiological pharmacokinetic model for artemisinin in healthy subjects incorporating autoinduction of metabolism and saturable first-pass hepatic extraction
- Human, Nor, NA
*Half-Life↝, BioAv↝, *Half-Life↓, BioAv↑, *Dose↝,
5423- ASTX,    Pharmacokinetic Profile of Astaxanthin Nanoemulsion Using HPLC (High-Performance Liquid Chromatography) With Oral Routes
- in-vivo, Nor, NA
*BioAv↓, *antiOx↑, *BioAv↑, *Half-Life↝,
5445- ATV,    Atorvastatin
- NA, Nor, NA
*cardioP↑, *LDL↓, HMG-CoA↓, Half-Life↝, BioAv↓, Dose↝,
5500- Ba,    Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single‐center, randomized, double‐blind, placebo‐controlled multiple‐ascending‐dose study
- Trial, Nor, NA
*toxicity↓, *BioAv↑, *Half-Life↝, *Dose↝,
5654- BNL,    Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio
- in-vivo, Nor, NA
*BioAv↑, *Half-Life↝, other↝,
5669- BNL,    Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol
- Review, Nor, NA - Review, AD, NA - Review, Stroke, NA
*eff↑, *eff↑, *toxicity↝, *Inflam↓, *Bacteria↓, *neuroP↑, *Half-Life↝, *BBB↑, *BioEnh↑, *P-gp↓, *CYP3A4↓, *ROS↓, *neuroP↑,
5672- Bor,    A comparative review of the pharmacokinetics of boric acid in rodents and humans
- in-vivo, Nor, NA
*Half-Life↝,
5879- CAR,    Pharmacokinetic analysis of thymol, carvacrol and diallyl disulfide after intramammary and topical applications in healthy organic dairy cattle
- in-vivo, Nor, NA
*Dose↝, Half-Life↝, Half-Life↝, Half-Life↝,
6029- CGA,    Pharmacokinetics of chlorogenic acids absorbed in human plasma and their metabolites following oral ingestion of coffee drink
- Trial, Nor, NA
*Dose↝, *BioAv↑, *Half-Life↝,
7417- CS,  CGA,    Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans
- Trial, Nor, NA
Dose↝, BioAv↝, Half-Life↝,
7418- CS,  CGA,  CA,  FA,    Absorption and metabolism of bioactive molecules after oral consumption of cooked edible heads of Cynara scolymus L. (cultivar Violetto di Provenza) in human subjects: a pilot study
- Study, Nor, NA
Half-Life↝, Half-Life↝, Half-Life↝,
6194- Cuc,    Pharmacokinetics of cucurbitacin B from Trichosanthes cucumerina L. in rats
- in-vivo, Nor, NA
*BioAv↓, *Half-Life↝, *AST∅, *ALAT∅, *RenoP↝, *Half-Life↝,
2809- CUR,    Comparative absorption of curcumin formulations
- in-vivo, Nor, NA
BioAv↑, BioAv↑, BioAv↑, BioAv↑, BioAv↑, BioAv↓, Half-Life↝,
6604- Ech,    Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion
- Human, Nor, NA
*BioAv↑, *Half-Life↝, *Dose↝, Dose?,
6782- EGCG,    Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability
- Human, Nor, NA
*Dose↝, BioAv↝, Half-Life↝,
2561- EGCG,  ASA,    Anti-platelet effects of epigallocatechin-3-gallate in addition to the concomitant aspirin, clopidogrel or ticagrelor treatment
- ex-vivo, Nor, NA
AntiAg↑, eff↑, Half-Life↝, other∅,
6992- Form,    Formononetin: pharmacological properties and therapeutic potential
- Review, Nor, NA
*BMD↑, *BioAv↑, *Half-Life↝, *BioAv↑,
7069- GABA,    United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA)
- Review, Nor, NA
*toxicity↓, *BP↓, *AntiDiabetic↑, *AntiCan↑, *antiOx↑, *Inflam↓, *AntiBio↑, *other↝, *cognitive↑, *GH↑, *Sleep↑, *BioAv↑, *Half-Life↝, *BBB↓, *eff↑,
7128- Ge-132,    Pharmacokinetics of germanium after po beta-carboxyethylgermanium sesquioxide in 24 Chinese volunteers
- Trial, Nor, NA
*Half-Life↝,
7123- GEO2,    Kinetics of germanium dioxide in rats
- in-vivo, Nor, NA
*Half-Life↝,
6572- Ger,    Pharmacokinetics of Geraniol and Its Metabolites in Mice After Oral Administration
- in-vivo, Nor, NA
BioAv↝, BBB↑, BioAv↝, Half-Life↝,
7135- GI,    Examination of the Pharmacokinetics of Active Ingredients of Ginger in Humans
- Trial, Nor, NA
*Dose↝, *Half-Life↝, *antiOx↑, *Inflam↓, *AntiTum↑, *Half-Life↓,
7280- Gins,    Pharmacokinetics of ginsenoside Rb1 and its metabolite compound K after oral administration of Korean Red Ginseng extract
- Trial, Nor, NA
*BioAv↑, *Half-Life↝, *eff↝,
7506- HCAs,    A Systematic Review and Comprehensive Evaluation of Human Intervention Studies to Unravel the Bioavailability of Hydroxycinnamic Acids
- Review, Nor, NA
*other↝, *BioAv↝, *Half-Life↝, *other↝, *Dose↝, *BioAv↝,
7349- HibSad,    Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract
- Trial, Nor, NA
*Dose↝, *Half-Life↓, *Half-Life↝, *BioAv↓, *antiOx↑, *BioAv↓,
7374- HOO,    Exploring Ozonated Vegetable Oils as Antimicrobial and Functional Agents in Food Systems: A Systematic Narrative Review
- Review, Nor, NA
*AntiBio↑, *eff↝, *Half-Life↝, *eff↑, *Phen↑, *antiOx↑, eff↝, eff↝,
7526- HT,    Hydroxytyrosol in functional hydroxytyrosol-enriched biscuits is highly bioavailable and decreases oxidised low density lipoprotein levels in humans
- Trial, Nor, NA
*Half-Life↝, *BioAv↑, *Dose↝, *BioAv↝,
7524- HT,    The Pharmaceutical Formulation Plays a Pivotal Role in Hydroxytyrosol Pharmacokinetics
- Trial, Nor, NA
*Dose↝, *BioAv↝, *Half-Life↝, *toxicity↓, *BioAv↝, *BioAv↝,
6537- MeSal,    The ancient drug salicylate directly activates AMP-activated protein kinase
- Review, Nor, NA
*BioAv↝, *AMPK↑, *Half-Life↝,
2442- RES,    High absorption but very low bioavailability of oral resveratrol in humans
- in-vitro, Nor, NA
BioAv↝, Half-Life↝, BioAv↓, eff↝,
3019- RosA,    Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid
- in-vivo, Nor, NA
*BioAv↝, *Half-Life↝, *Half-Life↑, *Half-Life↝, *BioAv↑,
3291- SIL,    Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases
- Review, Nor, NA
*antiOx↑, *ROS↓, *cardioP↑, *BioAv↓, *Half-Life↝, *other↑, IronCh↑,
6767- Thyme,    Thymol, thyme, and other plant sources: Health and potential uses
- Review, Nor, NA
*AntiBio↑, *Inflam↓, *Imm↑, *other↝, *Half-Life↝, *Obesity↓, *GutMicro↑,

Showing Research Papers: 1 to 39 of 39

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 39

Pathway results for Effect on Cancer / Diseased Cells:


Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

HMG-CoA↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,   other∅, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 6,   BioAv↝, 6,   Dose?, 1,   Dose↝, 2,   eff↑, 1,   eff↝, 3,   Half-Life↝, 14,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 3,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 6,   ROS↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT∅, 1,   AMPK↑, 1,   CYP3A4↓, 1,   LDL↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   other↝, 5,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GH↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Imm↑, 1,   Inflam↓, 4,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 6,   BioAv↑, 13,   BioAv↝, 8,   BioEnh↑, 1,   Dose?, 1,   Dose↑, 3,   Dose↝, 12,   eff↑, 4,   eff↝, 3,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 31,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT∅, 1,   AST∅, 1,   BMD↑, 1,   BP↓, 1,   GutMicro↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 1,   AntiTum↑, 1,   cardioP↑, 2,   cognitive↑, 1,   neuroP↑, 2,   Obesity↓, 1,   RenoP↝, 1,   Sleep↑, 1,   toxicity↓, 5,   toxicity↝, 2,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Phen↑, 1,  
Total Targets: 45

Scientific Paper Hit Count for: Half-Life, Half-Life
3 Chlorogenic acid
2 borneol
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 EGCG (Epigallocatechin Gallate)
2 HydroxyTyrosol
1 1,8-Cineole
1 5-Hydroxytryptophan
1 Auranofin
1 Astragalus
1 Silver-NanoParticles
1 Acetyl-l-carnitine
1 Artemisinin
1 Astaxanthin
1 Atorvastatin
1 Baicalein
1 Boron
1 Carvacrol
1 Caffeic acid
1 Ferulic acid
1 Cucurbitacin
1 Curcumin
1 Echinacea
1 Aspirin
1 Formononetin
1 Gamma-aminobutyric acid
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Germanium inorganic
1 Geraniol
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Hydroxycinnamic-acid
1 Hibiscus sabdariffa
1 High-Ozonide Oil
1 Methyl salicylate / Sweet Birch oil
1 Resveratrol
1 Rosmarinic acid
1 Silymarin (Milk Thistle) silibinin
1 Thyme
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:49  Cells:%  prod#:%  Target#:1109  State#:%  Dir#:4
  wNotes=0  sortOrder:rid,rpid

 

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