SOX9 Cancer Research Results

SOX9, SRY (sex determining region Y)-box 9: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
SOX9 (SRY-box transcription factor 9) is a transcription factor that plays a crucial role in various biological processes, including embryonic development, cell differentiation, and tissue homeostasis.
SOX9 has been implicated in the development and progression of several types of cancer, including breast, prostate, colorectal, and pancreatic cancers. It can promote tumor growth by regulating genes involved in cell proliferation, survival, and metastasis.
Chon, Chondrosarcoma: Click to Expand ⟱
Chondrosarcoma is a soft tissue sarcoma with a poor prognosis that is unresponsive to conventional chemotherapy. Chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. ~30% of bone sarcomas are chondrosarcomas. Resistant to chemotherapy and radiotherapy.
Scientific Papers found: Click to Expand⟱
3077- RES,    Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways
- in-vitro, Chon, HTB94
MMP2↓, MMP9↓, SOX9↑, MMPs↓, p‑p38↑, p‑JNK↓, NF-kB↓, HO-1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

HO-1↓, 1,  

Cell Death ⓘ

p‑JNK↓, 1,   p‑p38↑, 1,  

Kinase & Signal Transduction ⓘ

SOX9↑, 1,  

Migration ⓘ

MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SOX9, SRY (sex determining region Y)-box 9
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:5  Cells:%  prod#:%  Target#:289  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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