AST Cancer Research Results

AST, Aspartate Aminotransferase: Click to Expand ⟱
Source:
Type:
AST (Aspartate Aminotransferase) is an enzyme found in various tissues throughout the body, including the liver, heart, muscles, kidneys, and brain. Elevated levels of AST in the blood can be an indicator of tissue damage or disease.
AST levels can be elevated in certain types of cancer.
Used as a clinical biomarker for Liver function



CLL, Chronic Lymphocytic Leukemia: Click to Expand ⟱
CLL is a type of cancer that affects the lymphoid cells, which are a type of white blood cell. It is characterized by the accumulation of mature, but dysfunctional, lymphocytes in the bone marrow, lymph nodes, and spleen. CLL is typically a slow-growing disease, and many patients may not experience symptoms for years after diagnosis.


Scientific Papers found: Click to Expand⟱
7311- Gos,    Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials
- Review, CLL, NA
Dose↝, toxicity↓, PFS↓, OS↑, eff↑, BioAv↑, Bcl-2↓, ROS↑, MOMP↑, Dose↑, Casp3↑, Casp9↑, MMP↑, VEGF↓, APE1/APEX1↓, ChemoSen↑, RadioS↑, toxicity↑, AST↑, ALAT↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

APE1/APEX1↓, 1,   PFS↓, 1,  

Redox & Oxidative Stress(tgid=1)

ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT↑, 1,  

Cell Death(tgid=5)

Bcl-2↓, 1,   Casp3↑, 1,   Casp9↑, 1,   MOMP↑, 1,  

Angiogenesis & Vasculature(tgid=14)

VEGF↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   ChemoSen↑, 1,   Dose↑, 1,   Dose↝, 1,   eff↑, 1,   RadioS↑, 1,  

Clinical Biomarkers(tgid=22)

ALAT↑, 1,   AST↑, 1,  

Functional Outcomes(tgid=23)

OS↑, 1,   toxicity↓, 1,   toxicity↑, 1,  
Total Targets: 21

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: AST, Aspartate Aminotransferase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:50  Cells:%  prod#:%  Target#:691  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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