TNF-α Cancer Research Results

TNF-α, TNF-α: Click to Expand ⟱
Source: HalifaxProj (block)
Type:
Tumor Necrosis Factor-alpha (TNF-α) is a cytokine that plays a complex role in cancer biology. It is primarily produced by activated macrophages and is involved in systemic inflammation. TNF-α is a pro-inflammatory cytokine that can promote inflammation, which is a known factor in cancer development.
Overall, the expression of TNF-α in cancers is often linked to inflammation, tumor progression, and the tumor microenvironment.
Col, Colitis: Click to Expand ⟱
Colitis is an inflammation of the inner lining of the colon (large intestine). This condition can cause symptoms such as abdominal pain, diarrhea (often with blood or pus), fatigue, and sometimes weight loss. There are various types of colitis, including:

Ulcerative colitis: A chronic condition that causes long-lasting inflammation and ulcers in the digestive tract, primarily affecting the lining of the large intestine and rectum.
Infectious colitis: Caused by bacteria, viruses, or parasites, leading to temporary inflammation.
Ischemic colitis: Occurs when blood flow to a section of the colon is reduced, resulting in inflammation and damage to the colon tissue.
Microscopic colitis: Includes conditions like collagenous colitis and lymphocytic colitis, which are characterized by inflammation that can only be seen under a microscope.
Scientific Papers found: Click to Expand⟱
6275- DL,    Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans
- in-vivo, Col, NA
*TNF-α↓, *Inflam↓, *IL6↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Immune & Inflammatory Signaling ⓘ

IL6↓, 1,   Inflam↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  
Total Targets: 4

Scientific Paper Hit Count for: TNF-α, TNF-α
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:53  Cells:%  prod#:%  Target#:309  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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