| Source: |
| Type: |
| Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors. |
| Colorectal cancer is a broader term that encompasses both colon and rectal cancer. |
| 5167- | AL, | The Effects of Allicin, a Reactive Sulfur Species from Garlic, on a Selection of Mammalian Cell Lines |
| - | in-vitro, | Nor, | 3T3 | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Lung, | A549 | - | in-vitro, | CRC, | HT-29 |
| 1552- | Api, | Apigenin inhibits the growth of colorectal cancer through down-regulation of E2F1/3 by miRNA-215-5p |
| - | in-vitro, | CRC, | HCT116 |
| 2316- | Api, | The interaction between apigenin and PKM2 restrains progression of colorectal cancer |
| - | in-vitro, | CRC, | LS174T | - | in-vitro, | CRC, | HCT8 | - | in-vivo, | CRC, | NA |
| 175- | Api, | Apigenin up-regulates transgelin and inhibits invasion and migration of colorectal cancer through decreased phosphorylation of AKT |
| - | vitro+vivo, | CRC, | SW480 | - | vitro+vivo, | CRC, | DLD1 | - | vitro+vivo, | CRC, | LS174T |
| 172- | Api, | Apigenin suppresses colorectal cancer cell proliferation, migration and invasion via inhibition of the Wnt/β-catenin signaling pathway |
| - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | HTC15 |
| 1304- | ASA, | Aspirin Inhibits Colorectal Cancer via the TIGIT-BCL2-BAX pathway in T Cells |
| - | in-vitro, | CRC, | NA | - | in-vivo, | NA, | NA |
| 1179- | Ash, | Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity |
| - | in-vitro, | CRC, | HCT116 | - | in-vivo, | NA, | NA |
| 4806- | ASTX, | Astaxanthin's Impact on Colorectal Cancer: Examining Apoptosis, Antioxidant Enzymes, and Gene Expression |
| - | in-vitro, | CRC, | HCT116 |
| 1531- | Ba, | Proteomic analysis of the effects of baicalein on colorectal cancer cells |
| - | in-vitro, | CRC, | DLD1 | - | in-vitro, | CRC, | SW48 |
| 5547- | BBM, | Berbamine exerts anticancer effects on human colon cancer cells via induction of autophagy and apoptosis, inhibition of cell migration and MEK/ERK signalling pathway |
| - | in-vitro, | CRC, | HT29 |
| 1375- | BBR, | 13-[CH2CO-Cys-(Bzl)-OBzl]-Berberine: Exploring The Correlation Of Anti-Tumor Efficacy With ROS And Apoptosis Protein |
| - | in-vitro, | CRC, | HCT8 | - | in-vivo, | NA, | NA |
| 2337- | BBR, | Berberine Inhibited the Proliferation of Cancer Cells by Suppressing the Activity of Tumor Pyruvate Kinase M2 |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Cerv, | HeLa |
| 2682- | BBR, | Berberine Inhibited Growth and Migration of Human Colon Cancer Cell Lines by Increasing Phosphatase and Tensin and Inhibiting Aquaporins 1, 3 and 5 Expressions |
| - | in-vitro, | CRC, | HT29 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | HCT116 |
| 4658- | BBR, | Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m6A Methylation |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT29 |
| 5176- | BBR, | Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice |
| - | vitro+vivo, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | LoVo |
| 2740- | BetA, | Effects and mechanisms of fatty acid metabolism-mediated glycolysis regulated by betulinic acid-loaded nanoliposomes in colorectal cancer |
| - | in-vitro, | CRC, | HCT116 |
| 5707- | Brut, | Targeting Redox Homeostasis and Cell Survival Signaling with a Flavonoid-Rich Extract of Bergamot Juice in In Vitro and In Vivo Colorectal Cancer Models |
| - | in-vitro, | CRC, | HCT116 |
| 5737- | Buty, | Butyrate Suppresses the Proliferation of Colorectal Cancer Cells via Targeting Pyruvate Kinase M2 and Metabolic Reprogramming |
| - | in-vitro, | CRC, | HCT116 |
| 5747- | CA, | Caffeic Acid Enhances Anticancer Drug-induced Apoptosis in Acid-adapted HCT116 Colon Cancer Cells |
| - | in-vitro, | CRC, | NA |
| 17- | CBC/D, | CBC-1 as a Cynanbungeigenin C derivative inhibits the growth of colorectal cancer through targeting Hedgehog pathway component GLI 1 |
| - | in-vivo, | CRC, | NA |
| 1055- | Cin, | Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1 |
| - | vitro+vivo, | Melanoma, | NA | - | vitro+vivo, | CRC, | NA | - | vitro+vivo, | lymphoma, | NA |
| 6179- | Cro, | Crocetin suppresses the growth and migration in HCT-116 human colorectal cancer cells by activating the p-38 MAPK signaling pathway |
| - | NA, | CRC, | HCT116 |
| 6192- | Cuc, | Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway |
| - | vitro+vivo, | CRC, | NA |
| 2974- | CUR, | Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT29 | - | in-vitro, | CRC, | HCT15 | - | in-vitro, | CRC, | COLO205 | - | in-vitro, | CRC, | SW-620 | - | in-vivo, | NA, | NA |
| 438- | CUR, | Curcumin Reduces Colorectal Cancer Cell Proliferation and Migration and Slows In Vivo Growth of Liver Metastases in Rats |
| - | vitro+vivo, | CRC, | CC531 |
| 450- | CUR, | Curcumin may be a potential adjuvant treatment drug for colon cancer by targeting CD44 |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HCT8 |
| 449- | CUR, | Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a |
| - | vitro+vivo, | CRC, | SW480 |
| - | in-vitro, | CRC, | SW480 |
| 442- | CUR, | 5-FU, | Curcumin may reverse 5-fluorouracil resistance on colonic cancer cells by regulating TET1-NKD-Wnt signal pathway to inhibit the EMT progress |
| - | in-vitro, | CRC, | HCT116 |
| 440- | CUR, | Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells |
| - | vitro+vivo, | CRC, | SW480 | - | vitro+vivo, | CRC, | HT-29 |
| 3213- | EGCG, | Rad, | Epigallocatechin-3-gallate Enhances Radiation Sensitivity in Colorectal Cancer Cells Through Nrf2 Activation and Autophagy |
| - | in-vitro, | CRC, | HCT116 |
| 811- | GAR, | Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells |
| - | in-vitro, | CRC, | HT-29 |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | LoVo | - | in-vivo, | CRC, | HCT116 |
| 2076- | PB, | Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT29 |
| 1678- | PBG, | 5-FU, | sericin, | In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mTOR pathway |
| - | in-vitro, | CRC, | Caco-2 | - | in-vivo, | NA, | NA |
| 5214- | PI, | Piperine induces autophagy of colon cancer cells: Dual modulation of AKT/mTOR signaling pathway and ROS production |
| - | vitro+vivo, | CRC, | HCT116 | - | in-vitro, | CRC, | SW48 | - | in-vitro, | CRC, | SW-620 |
| 1016- | PI, | Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | DLD1 |
| 5164- | PLB, | Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor-2 |
| - | vitro+vivo, | CRC, | NA | - | in-vitro, | Pca, | NA |
| 44- | QC, | Preclinical Colorectal Cancer Chemopreventive Efficacy and p53-Modulating Activity of 3′,4′,5′-Trimethoxyflavonol, a Quercetin Analog |
| - | in-vivo, | CRC, | HCT116 |
| 2330- | RES, | Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission |
| - | in-vitro, | CRC, | DLD1 | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | BC, | MCF-7 |
| 879- | RES, | Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it |
| - | in-vitro, | CRC, | HCT116 |
| 993- | RES, | Resveratrol reverses the Warburg effect by targeting the pyruvate dehydrogenase complex in colon cancer cells |
| - | in-vitro, | CRC, | Caco-2 | - | in-vivo, | Nor, | HCEC 1CT |
| 4902- | Sal, | OXA, | Salinomycin and oxaliplatin synergistically enhances cytotoxic effect on human colorectal cancer cells in vitro and in vivo |
| - | vitro+vivo, | CRC, | NA |
| 4909- | Sal, | Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model |
| - | vitro+vivo, | CRC, | NA |
| 1457- | SFN, | Sulforaphane Inhibits IL-1β-Induced IL-6 by Suppressing ROS Production, AP-1, and STAT3 in Colorectal Cancer HT-29 Cells |
| - | in-vitro, | CRC, | HT-29 |
| 3297- | SIL, | Rad, | Studies on radiation sensitization efficacy by silymarin in colon carcinoma cells |
| - | in-vitro, | CRC, | HCT15 | - | in-vitro, | CRC, | RKO |
| 5101- | SK, | Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis |
| - | vitro+vivo, | CRC, | SW-620 | - | vitro+vivo, | CRC, | HCT116 |
| 965- | SK, | Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW-620 |
| 4723- | SSE, | Selenium Induces Ferroptosis in Colorectal Cancer Cells via Direct Interaction with Nrf2 and Gpx4 |
| - | in-vitro, | CRC, | HCT116 |
| 5091- | SSE, | Superoxide-mediated ferroptosis in human cancer cells induced by sodium selenite |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Pca, | PC3 | - | in-vitro, | CRC, | HT-29 | - | in-vitro, | Nor, | SVGp12 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:6 Cells:% prod#:% Target#:327 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid