CYP11A1 Cancer Research Results

CYP11A1, CYP11A1: Click to Expand ⟱

Source:

Type:

CYP11A1: gene that encodes a cytochrome P450 enzyme that catalyzes the conversion of cholesterol to pregnenolone, a precursor of steroid hormones.

Elevated CYP11A1 levels have been observed in cancer, and its expression may correlate with tumor aggressiveness and patient survival.

CRC, Colorectal Cancer: Click to Expand ⟱

Colorectal cancer is a broader term that encompasses both colon and rectal cancer.

Scientific Papers found: Click to Expand⟱

1496-

SFN,

VitD3,

Association between histone deacetylase activity and vitamin D-dependent gene expressions in relation to sulforaphane in human colorectal cancer cells

in-vitro,

CRC,

Caco-2

24 h to vitamin D (100 nmol L-1 ) either alone or in combination with SFN and trichostatin A (20 and 1 μmol L-1 , respectively)

eff↑, VDR↑, CYP11A1↓, HDAC↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Proliferation, Differentiation & Cell State ⓘ

HDAC↓, 1, VDR↑, 1,

Hormonal & Nuclear Receptors ⓘ

CYP11A1↓, 1,

Drug Metabolism & Resistance ⓘ

eff↑, 1,
Total Targets: 4

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: CYP11A1, CYP11A1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells