| Source: |
| Type: |
| Cell Viability |
| Colorectal cancer is a broader term that encompasses both colon and rectal cancer. |
| 4403- | AgNPs, | Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment |
| - | in-vitro, | GBM, | U251 | - | in-vitro, | GBM, | U87MG | - | in-vitro, | GBM, | GL26 | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | CRC, | RKO |
| 5167- | AL, | The Effects of Allicin, a Reactive Sulfur Species from Garlic, on a Selection of Mammalian Cell Lines |
| - | in-vitro, | Nor, | 3T3 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | Lung, | A549 | - | in-vitro, | CRC, | HT-29 |
| 1008- | Api, | Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 |
| 2475- | Ba, | Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/STAT3/GPX4 axis |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | DLD1 | - | in-vivo, | NA, | NA |
| 5539- | BBM, | Berbamine suppresses cell viability and induces apoptosis in colorectal cancer via activating p53-dependent apoptotic signaling pathway |
| - | vitro+vivo, | CRC, | SW480 |
| 5547- | BBM, | Berbamine exerts anticancer effects on human colon cancer cells via induction of autophagy and apoptosis, inhibition of cell migration and MEK/ERK signalling pathway |
| - | in-vitro, | CRC, | HT29 |
| 6498- | BCP, | β-Caryophyllene induces apoptosis and inhibits cell proliferation by deregulation of STAT-3/mTOR/AKT signaling in human bladder cancer cells: An in vitro study |
| - | in-vitro, | CRC, | T24/HTB-9 | - | in-vitro, | Bladder, | 5637 |
| 2734- | BetA, | Betulinic Acid Modulates the Expression of HSPA and Activates Apoptosis in Two Cell Lines of Human Colorectal Cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 |
| 5696- | BRU, | The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer |
| - | in-vitro, | CRC, | HCT116 |
| 5877- | CA, | Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells |
| - | in-vitro, | CRC, | HCT116 |
| 5866- | CA, | Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | SW480 | - | in-vitro, | Colon, | HT29 |
| 5198- | CAP, | Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines |
| - | in-vitro, | CRC, | LoVo | - | in-vitro, | CRC, | Colo320 |
| 6630- | CGA, | In Vitro and In Silico Study on the Impact of Chlorogenic Acid in Colorectal Cancer Cells: Proliferation, Apoptosis, and Interaction with β-Catenin and LRP6 |
| - | in-vitro, | CRC, | HT29 | - | in-vitro, | CRC, | SW480 |
| 6628- | Cic, | The Prevention and Treatment of Colorectal Cancer by Traditional Plants |
| - | Review, | CRC, | NA |
| 6312- | Cro, | Crocin from Crocus Sativus Possesses Significant Anti-Proliferation Effects on Human Colorectal Cancer Cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW48 | - | in-vitro, | CRC, | HT29 |
| 6309- | Cro, | Crocin exerts anti-tumor effect in colon cancer cells via repressing the JaK pathway |
| - | in-vitro, | CRC, | HCT116 |
| 7414- | CS, | Pro-Apoptotic Activity of Artichoke Leaf Extracts in Human HT-29 and RKO Colon Cancer Cells |
| - | in-vitro, | Colon, | HT29 | - | in-vitro, | CRC, | RKO |
| 7445- | CYN, | Cynaropicrin Shows Antitumor Progression Potential in Colorectal Cancer Through Mediation of the LIFR/STATs Axis |
| - | vitro+vivo, | CRC, | RKO | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | DLD1 |
| 1878- | DCA, | 5-FU, | Synergistic Antitumor Effect of Dichloroacetate in Combination with 5-Fluorouracil in Colorectal Cancer |
| - | in-vitro, | CRC, | LS174T | - | in-vitro, | CRC, | LoVo | - | in-vitro, | CRC, | SW-620 | - | in-vitro, | CRC, | HT-29 |
| 6745- | DHA, | Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells |
| - | in-vitro, | CRC, | HT29 |
| 6269- | DL, | Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells |
| - | in-vitro, | CRC, | LS174T |
| 6358- | DRE, | Dandelion root extracts and taraxasterol inhibit LPS‑induced colorectal cancer cell viability by blocking TLR4‑NFκB‑driven ACE2 and TMPRSS2 pathways |
| - | in-vitro, | CRC, | NA |
| 6607- | Ech, | Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines |
| - | in-vitro, | PC, | MIA PaCa-2 | - | in-vitro, | CRC, | Colo320 |
| 3241- | EGCG, | Epigallocatechin gallate triggers apoptosis by suppressing de novo lipogenesis in colorectal carcinoma cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT29 | - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Liver, | HUH7 |
| 1321- | EMD, | Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model |
| - | in-vitro, | CRC, | LS1034 | - | in-vivo, | NA, | NA |
| 5223- | EMD, | Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways |
| - | in-vitro, | CRC, | DLD1 | - | in-vitro, | Nor, | CCD841 |
| 6839- | EVO, | Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G2/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine |
| - | in-vitro, | CRC, | COLO205 | - | in-vitro, | Colon, | HT29 |
| 6965- | Form, | Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways |
| - | in-vitro, | CRC, | HCT116 |
| 7014- | Fuc, | 5-FU, | Low-Molecular-Weight Fucoidan as Complementary Therapy of Fluoropyrimidine-Based Chemotherapy in Colorectal Cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | Caco-2 |
| 7216- | GBE, | Cytotoxic effect of Ginkgo biloba kernel extract on HCT116 and A2058 cancer cell lines |
| - | in-vitro, | Melanoma, | A2058 | - | in-vitro, | CRC, | HCT116 |
| 7211- | GBE, | Ginkgo Biflavones Cause p53 Wild-Type Dependent Cell Death in a Transcription-Independent Manner of p53 |
| - | in-vitro, | CRC, | HCT116 |
| 7252- | Gink, | STEAP2-associated modulation of PI3K/AKT/mTOR signaling contributes to ginkgetin-induced apoptosis in bladder cancer cells |
| - | in-vitro, | Bladder, | 5637 | - | in-vitro, | CRC, | T24/HTB-9 | - | in-vitro, | Bladder, | J82 | - | in-vitro, | Nor, | SV-HUC-1 |
| 857- | Gra, | The Value of Caspase-3 after the Application of Annona muricata Leaf Extract in COLO-205 Colorectal Cancer Cell Line |
| - | in-vitro, | CRC, | COLO205 |
| 7539- | HT, | Polyphenols Extracts from Oil Production Waste Products (OPWPs) Reduce Cell Viability and Exert Anti-Inflammatory Activity via PPARγ Induction in Colorectal Cancer Cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | LoVo |
| 2177- | itraC, | Itraconazole improves survival outcomes in patients with colon cancer by inducing autophagic cell death and inhibiting transketolase expression |
| - | Study, | Colon, | NA | - | in-vitro, | CRC, | COLO205 | - | in-vitro, | CRC, | HCT116 |
| 2915- | LT, | Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells |
| - | in-vitro, | Colon, | HT29 | - | in-vitro, | CRC, | SNU-407 | - | in-vitro, | Nor, | FHC |
| 6538- | MeSal, | ASA, | Salicylate induces AMPK and inhibits c-MYC to activate a NRF2/ARE/miR-34a/b/c cascade resulting in suppression of colorectal cancer metastasis |
| - | in-vitro, | CRC, | NA |
| 1388- | Sco, | Scoulerine promotes cell viability reduction and apoptosis by activating ROS-dependent endoplasmic reticulum stress in colorectal cancer cells |
| - | in-vitro, | CRC, | NA |
| 1480- | SFN, | Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells |
| - | in-vitro, | CRC, | HCT116 |
| - | in-vitro, | CRC, | HCT116 |
| 2007- | SK, | Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells |
| - | in-vitro, | lymphoma, | U937 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | SkBr3 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | OS, | U2OS | - | NA, | Nor, | RPE-1 |
| 6432- | T4O, | Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species |
| - | in-vitro, | CRC, | HCT116 |
| 5222- | TQ, | Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-κB |
| - | in-vitro, | CRC, | COLO205 | - | in-vitro, | CRC, | HCT116 |
| 3413- | TQ, | Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase |
| - | in-vitro, | CRC, | HCT116 |
| 3141- | VitC, | High-dose Vitamin C inhibits PD-L1 expression by activating AMPK in colorectal cancer |
| - | in-vitro, | CRC, | HCT116 |
| 4888- | ZER, | 5-FU, | Modulation of the tumor microenvironment by zerumbone and 5-fluorouracil in colorectal cancer by target in cancer-associated fibroblasts |
| - | in-vitro, | CRC, | CT26 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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