EF-1α Cancer Research Results

EF-1α, elongation factor 1 alpha: Click to Expand ⟱
Source:
Type:
Furthermore, overexpression of EF-1α is correlated with increased cell proliferation and oncogenic transformation in breast cancers (20) and is positively associated with prostate cancer progression (21).
a protein that plays a crucial role in the process of protein synthesis (translation) in eukaryotic cells. It is involved in the delivery of aminoacyl-tRNA to the ribosome, facilitating the elongation phase of translation.
EF-1α is often overexpressed in various types of cancer. This overexpression can contribute to the increased protein synthesis required for rapid cell proliferation and tumor growth.
CRC, Colorectal Cancer: Click to Expand ⟱
Colorectal cancer is a broader term that encompasses both colon and rectal cancer.
Scientific Papers found: Click to Expand⟱
7099- Geld,    Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation
- in-vitro, CRC, DLD1
RadioS↑, EF-1α↓, Akt↓, HSP90↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death(tgid=5) ⓘ

Akt↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

EF-1α↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP90↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

RadioS↑, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: EF-1α, elongation factor 1 alpha
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:6  Cells:%  prod#:%  Target#:91  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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