miR-497 Cancer Research Results

miR-497, miR-497: Click to Expand ⟱
Source:
Type:
miR-497 has been identified as a tumor suppressor miRNA, and its downregulation has been observed in various types of cancer, including breast, lung, colon, and ovarian cancer. The expression of miR-497 is often reduced in cancer cells, which can lead to the upregulation of target genes involved in cell proliferation, apoptosis, and metastasis.
miR-497 targets several oncogenes, including: BCL2, cyclin D1, cyclin E1, IGF1R.
CRC, Colorectal Cancer: Click to Expand ⟱
Colorectal cancer is a broader term that encompasses both colon and rectal cancer.
Scientific Papers found: Click to Expand⟱
444- CUR,  Cisplatin,    LncRNA KCNQ1OT1 is a key factor in the reversal effect of curcumin on cisplatin resistance in the colorectal cancer cells
- vitro+vivo, CRC, HCT8
TumVol↓, Apoptosis↑, Bcl-2↓, Cyt‑c↑, BAX↑, cl‑Casp3↑, cl‑PARP1↑, miR-497↑, KCNQ1OT1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   cl‑Casp3↑, 1,   Cyt‑c↑, 1,   miR-497↑, 1,  

Transcription & Epigenetics ⓘ

KCNQ1OT1↓, 1,  

DNA Damage & Repair ⓘ

cl‑PARP1↑, 1,  

Functional Outcomes ⓘ

TumVol↓, 1,  
Total Targets: 9

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-497, miR-497
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:6  Cells:%  prod#:%  Target#:701  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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