p16 Cancer Research Results

p16, protein 16: Click to Expand ⟱
Source:
Type: tumor suppressor protein
p16 is a protein that plays a crucial role in regulating the cell cycle and preventing cancer. It is a tumor suppressor protein that helps to prevent the uncontrolled growth of cells. p16 is a cyclin-dependent kinase inhibitor, which means that it helps to regulate the activity of certain enzymes (cyclin-dependent kinases) that drive the cell cycle forward. By inhibiting these enzymes, p16 helps to slow down or stop the cell cycle, giving the cell time to repair any DNA damage that may have occurred.
p16 has been shown to be inactivated in many types of cancer, including breast, lung, and colon cancer.
CRC, Colorectal Cancer: Click to Expand ⟱
Colorectal cancer is a broader term that encompasses both colon and rectal cancer.
Scientific Papers found: Click to Expand⟱
7411- CS,    Long Term Exposure to Polyphenols of Artichoke (Cynara scolymus L.) Exerts Induction of Senescence Driven Growth Arrest in the MDA-MB231 Human Breast Cancer Cell Line
- in-vitro, BC, MDA-MB-231 - in-vitro, CRC, HCT116
AntiCan↑, chemoPv↑, Apoptosis↑, TumCI↓, Casp↑, p16↑, P21↑, TumCCA↑, ROS↓, eff↓, TumCD↑, TumCG↓, cellSen↑, *ROS↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   Casp↑, 1,   TumCD↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p16↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,  

Migration(tgid=13) ⓘ

TumCI↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

cellSen↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   chemoPv↑, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: p16, protein 16
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:6  Cells:%  prod#:%  Target#:727  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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