miR-145 Cancer Research Results

miR-145, miR-145: Click to Expand ⟱
Source:
Type: tumor suppressor miRNA
miR-145 has been identified as a tumor suppressor miRNA, and its downregulation has been observed in various types of cancer.
CRC, Colorectal Cancer: Click to Expand ⟱
Colorectal cancer is a broader term that encompasses both colon and rectal cancer.
Scientific Papers found: Click to Expand⟱
679- EGCG,  5-FU,    Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer
- in-vitro, CRC, NA
NOTCH1↓, BMI1↓, SUZ12↓, EZH2↓, miR-34a↑, miR-200c↑, miR-145↑, CSCs↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics ⓘ

EZH2↓, 1,   miR-145↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

BMI1↓, 1,   CSCs↓, 1,   miR-34a↑, 1,   NOTCH1↓, 1,   SUZ12↓, 1,  

Migration ⓘ

miR-200c↑, 1,  

Clinical Biomarkers ⓘ

EZH2↓, 1,   SUZ12↓, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-145, miR-145
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:6  Cells:%  prod#:%  Target#:839  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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