HATs Cancer Research Results
HATs, histone acetyltransferases: Click to Expand ⟱
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Histone acetyltransferases (HATs) are a family of enzymes that play a crucial role in the regulation of gene expression by modifying chromatin structure. HATs transfer acetyl groups to the lysine residues of histone proteins, which are the main components of chromatin. This modification, known as histone acetylation, leads to the relaxation of chromatin structure, allowing for increased access of transcription factors to DNA and promoting gene expression.
HATs is overexpressed in cancers with poor prognosis.
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CRC, Colorectal Cancer: Click to Expand ⟱
Colorectal cancer is a broader term that encompasses both colon and rectal cancer.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
CRC, |
HCT116 |
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in-vitro, |
CRC, |
HT29 |
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HDAC↓, Warburg↓, TumCP⇅, HATs↑, BioAv↓, other↝, Risk↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Core Metabolism/Glycolysis ⓘ
Warburg↓, 1,
Transcription & Epigenetics ⓘ
HATs↑, 1, other↝, 1,
Proliferation, Differentiation & Cell State ⓘ
HDAC↓, 1,
Migration ⓘ
TumCP⇅, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1,
Functional Outcomes ⓘ
Risk↓, 1,
Total Targets: 7
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: HATs, histone acetyltransferases
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:6 Cells:% prod#:% Target#:886 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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