FABP4 Cancer Research Results

FABP4, Fatty acid-binding proteins 4: Click to Expand ⟱
Source:
Type:
Belongs to a family of intracellular lipid-binding protein, can bind hydrophobic ligands to regulate lipid trafficking and metabolism.
Has been found to be upregulated in many malignant solid tumors, and correlated with poor prognosis.


Obesity, Obesity: Click to Expand ⟱
Obesity


Scientific Papers found: Click to Expand⟱
3521- Bor,    A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway
- in-vitro, Obesity, 3T3
*CEBPA↓, *PPARγ↓, *FASN↓, *SREBP1↓, *FABP4↓, *GLUT4↓, *β-catenin/ZEB1↑, *MMP2↓, *FGF↑, *Ca+2?,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis

FABP4↓, 1,   FASN↓, 1,   PPARγ↓, 1,   SREBP1↓, 1,  

Proliferation, Differentiation & Cell State

CEBPA↓, 1,   FGF↑, 1,  

Migration

Ca+2?, 1,   MMP2↓, 1,   β-catenin/ZEB1↑, 1,  

Barriers & Transport

GLUT4↓, 1,  
Total Targets: 10

Scientific Paper Hit Count for: FABP4, Fatty acid-binding proteins 4
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:63  Cells:%  prod#:%  Target#:551  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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