cognitive Cancer Research Results

cognitive, cognitive: Click to Expand ⟱
Source:
Type:
Cognitive


Sepsis, Sepsis: Click to Expand ⟱
Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. This initial stage of sepsis is followed by suppression of the immune system. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion.


Scientific Papers found: Click to Expand⟱
3667- ART/DHA,    Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in microglia
- Review, Sepsis, NA
*cognitive↑, *neuroP↑, *TNF-α↓, *IL6↓, *NF-kB↓, *AMPK↑, *ROS↓, *Akt↑, *MCP1↓, *MIP2↓, *TGF-β↑, *Inflam↓,
4235- H2,    PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression
- in-vivo, Sepsis, NA
*PPARα↑, *CREB↑, *BDNF↑, *OS↑, *cognitive↑,
4234- H2,    Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice
- in-vivo, Sepsis, NA
*cognitive↑, *DNMT1↓, *DNMT3A↓, *BDNF↑,
3022- RosA,    Rosmarinic acid against cognitive impairment via RACK1/HIF-1α regulated microglial polarization in sepsis-surviving mice
- in-vitro, Sepsis, NA
*cognitive↑, *neuroP↑, *GlucoseCon↑, *Hif1a↓,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

ROS↓, 1,  

Core Metabolism/Glycolysis

AMPK↑, 1,   CREB↑, 1,   GlucoseCon↑, 1,   PPARα↑, 1,  

Cell Death

Akt↑, 1,  

DNA Damage & Repair

DNMT1↓, 1,   DNMT3A↓, 1,  

Migration

TGF-β↑, 1,  

Angiogenesis & Vasculature

Hif1a↓, 1,  

Immune & Inflammatory Signaling

IL6↓, 1,   Inflam↓, 1,   MCP1↓, 1,   MIP2↓, 1,   NF-kB↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission

BDNF↑, 2,  

Clinical Biomarkers

IL6↓, 1,  

Functional Outcomes

cognitive↑, 4,   neuroP↑, 2,   OS↑, 1,  
Total Targets: 21

Scientific Paper Hit Count for: cognitive, cognitive
2 Hydrogen Gas
1 Artemisinin
1 Rosmarinic acid
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:65  Cells:%  prod#:%  Target#:557  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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