chemoPv Cancer Research Results

chemoPv, ChemoPreventive: Click to Expand ⟱
Source:
Type:
Chemopreventive: An agent that lowers the probability of cancer development or delays progression from premalignant states.
Mechanisms
-Reduce DNA damage / mutagenesis
-Enhance detoxification or repair
-Modulate hormones or inflammation
-Promote differentiation or apoptosis of abnormal cells


MM, Malignant Mesothelioma: Click to Expand ⟱
Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs. The area most commonly affected is the lining of the lungs and chest wall.
Scientific Papers found: Click to Expand⟱
6512- BCP,    Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells
- in-vitro, MM, NA
CB2 / CNR2↑, BAX↑, Bcl-2↓, Casp3↑, TumCP↓, Apoptosis↑, Akt↓, Wnt↓, β-catenin/ZEB1↓, TumCCA↑, Inflam↓, chemoPv↑, neuroP↑, *BioAv↝, CB2 / CNR2↑, tumCV↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

CB2 / CNR2↑, 2,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Wnt↓, 1,  

Migration ⓘ

TumCP↓, 1,   β-catenin/ZEB1↓, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Functional Outcomes ⓘ

chemoPv↑, 1,   neuroP↑, 1,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


Drug Metabolism & Resistance ⓘ

BioAv↝, 1,  
Total Targets: 1

Scientific Paper Hit Count for: chemoPv, ChemoPreventive
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:70  Cells:%  prod#:%  Target#:1417  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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