toxicity Cancer Research Results
toxicity, toxicity: Click to Expand ⟱
Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease
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Scientific Papers found: Click to Expand⟱
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Review, |
Var, |
NA |
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Park, |
NA |
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AD, |
NA |
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AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL6↑, *MMP13↓,
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Nor, |
NA |
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AD, |
NA |
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Park, |
NA |
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Stroke, |
NA |
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*Inflam↓, *antiOx↑, *AntiBio↑, *hepatoP↑, *AntiCan↑, *other↝, *toxicity↓, *Wound Healing↓, *Dose↝, *Dose↝, *eff↝, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *AST↓, *ALAT↓,
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Review, |
AD, |
NA |
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Park, |
NA |
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*memory↑, *cognitive↑, *ROS↓, *Inflam↓, *motorD↑, *toxicity↓, *TRPV3↑, *other↓, *antiOx↑, *LDL↓, *COX2↓, *PPARα↑, *NO↓, *AChE↓, *eff↑, *SOD↑, *Catalase↑, *neuroP↑, *BioAv↝, *BBB↑, *BioAv↑,
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Review, |
Var, |
NA |
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Review, |
AD, |
NA |
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Review, |
Park, |
NA |
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*Dose↝, *BioEnh↑, *BBB↑, *ROS↓, *GSH↑, *SOD↑, *GSR↑, *NO↓, *P450↓, OS↑, TumCG↓, *GutMicro↑, *Pain↓, *neuroP↑, *AChE↓, *BDNF↑, *Bacteria↓, *AntiFungal↑, *toxicity↓,
Showing Research Papers: 1 to 4 of 4
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4
Pathway results for Effect on Cancer / Diseased Cells:
Mitochondria & Bioenergetics ⓘ
XIAP↓, 1,
Cell Death ⓘ
Akt↓, 1, Apoptosis↑, 1, Bak↓, 1, BAX↑, 1, Bcl-2↓, 1, BID↑, 1, Casp3↑, 1, Casp8↑, 1, Casp9↑, 1, Cyt‑c↑, 1, Fas↑, 1,
Kinase & Signal Transduction ⓘ
HER2/EBBR2↓, 1,
DNA Damage & Repair ⓘ
P53↑, 1, PARP↑, 1,
Cell Cycle & Senescence ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State ⓘ
FGF↓, 1, TumCG↓, 1,
Migration ⓘ
CEA↓, 1, TIMP2↑, 1,
Angiogenesis & Vasculature ⓘ
EGFR↑, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, NF-kB↑, 1,
Drug Metabolism & Resistance ⓘ
RadioS↑, 1,
Clinical Biomarkers ⓘ
CEA↓, 1, EGFR↑, 1, HER2/EBBR2↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, OS↑, 1,
Total Targets: 29
Pathway results for Effect on Normal Cells:
NA, unassigned ⓘ
AntiBio↑, 3,
Redox & Oxidative Stress ⓘ
antiOx↑, 3, Catalase↑, 3, GSH↑, 3, GSR↑, 1, Keap1↑, 1, lipid-P↓, 1, MDA↓, 1, ROS↓, 4, SOD↑, 4, TBARS↓, 1, uricA↓, 1,
Mitochondria & Bioenergetics ⓘ
ATP↑, 1, MMP↑, 1,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1, LDL↓, 1, PPARα↑, 1,
Cell Death ⓘ
Apoptosis↓, 1, BAX↓, 1, Bcl-2↑, 1, Casp3↓, 1, Cyt‑c↓, 1, iNOS↓, 2,
Kinase & Signal Transduction ⓘ
TRPV3↑, 1,
Transcription & Epigenetics ⓘ
other↓, 1, other↝, 2,
Migration ⓘ
MMP13↓, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 2,
Barriers & Transport ⓘ
BBB↑, 3, GastroP↑, 1,
Immune & Inflammatory Signaling ⓘ
CD4+↑, 1, COX2↓, 3, IL1β↓, 1, IL6↓, 2, IL6↑, 1, Imm↑, 1, Inflam↓, 3, TNF-α↓, 3,
Synaptic & Neurotransmission ⓘ
AChE↓, 3, BChE↓, 1, BDNF↑, 1,
Protein Aggregation ⓘ
Aβ↓, 1, BACE↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↑, 3, BioAv↝, 1, BioEnh↑, 1, Dose↝, 3, eff↑, 2, eff↝, 1, P450↓, 1,
Clinical Biomarkers ⓘ
ALAT↓, 1, AST↓, 1, creat↓, 1, GutMicro↑, 1, IL6↓, 2, IL6↑, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, cardioP↑, 2, cognitive↑, 1, hepatoP↑, 1, memory↑, 1, motorD↑, 2, neuroP↑, 3, Pain↓, 2, RenoP↑, 1, toxicity↓, 4, Wound Healing↓, 1,
Infection & Microbiome ⓘ
AntiFungal↑, 2, Bacteria↓, 1, CD8+↑, 1,
Total Targets: 70
Scientific Paper Hit Count for: toxicity, toxicity
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:75 Cells:% prod#:% Target#:1025 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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