Bak Cancer Research Results
Bak, BAK or BAK1: Click to Expand ⟱
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Bak (also known as BAK or BAK1) is a protein that plays a crucial role in regulating cell death.
In cancer, the Bak protein is often inactivated or downregulated, allowing cancer cells to evade apoptosis and continue to proliferate uncontrollably.
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Park, Parkinson's Disease (PD): Click to Expand ⟱
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, and is due to the degeneration of dopaminergic neurons. It is multifactorial, caused by genetic and environmental factors and currently has no definitive cure.
-CoQ10 deficiency was observed at a higher frequency in Parkinson's disease
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Scientific Papers found: Click to Expand⟱
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AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL6↑, *MMP13↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Mitochondria & Bioenergetics(tgid=3) ⓘ
XIAP↓, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 1, Apoptosis↑, 1, Bak↓, 1, BAX↑, 1, Bcl-2↓, 1, BID↑, 1, Casp3↑, 1, Casp8↑, 1, Casp9↑, 1, Cyt‑c↑, 1, Fas↑, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
HER2/EBBR2↓, 1,
DNA Damage & Repair(tgid=10) ⓘ
P53↑, 1, PARP↑, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
FGF↓, 1,
Migration(tgid=13) ⓘ
CEA↓, 1, TIMP2↑, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
EGFR↑, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX2↓, 1, NF-kB↑, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
RadioS↑, 1,
Clinical Biomarkers(tgid=22) ⓘ
CEA↓, 1, EGFR↑, 1, HER2/EBBR2↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 1,
Total Targets: 27
Pathway results for Effect on Normal Cells:
NA, unassigned(tgid=0) ⓘ
AntiBio↑, 2,
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 1, Catalase↑, 2, GSH↑, 2, Keap1↑, 1, lipid-P↓, 1, MDA↓, 1, ROS↓, 1, SOD↑, 2, TBARS↓, 1, uricA↓, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ATP↑, 1, MMP↑, 1,
Cell Death(tgid=5) ⓘ
Apoptosis↓, 1, BAX↓, 1, Bcl-2↑, 1, Casp3↓, 1, Cyt‑c↓, 1, iNOS↓, 2,
Migration(tgid=13) ⓘ
MMP13↓, 1,
Barriers & Transport(tgid=15) ⓘ
BBB↑, 1, GastroP↑, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CD4+↑, 1, COX2↓, 2, IL1β↓, 1, IL6↓, 1, IL6↑, 1, Imm↑, 1, Inflam↓, 1, TNF-α↓, 2,
Synaptic & Neurotransmission(tgid=18) ⓘ
AChE↓, 1, BChE↓, 1,
Protein Aggregation(tgid=19) ⓘ
Aβ↓, 1, BACE↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↑, 2, eff↑, 1,
Clinical Biomarkers(tgid=22) ⓘ
creat↓, 1, IL6↓, 1, IL6↑, 1,
Functional Outcomes(tgid=23) ⓘ
cardioP↑, 2, motorD↑, 1, neuroP↑, 1, Pain↓, 1, RenoP↑, 1, toxicity↓, 1,
Infection & Microbiome(tgid=24) ⓘ
AntiFungal↑, 1, CD8+↑, 1,
Total Targets: 47
Scientific Paper Hit Count for: Bak, BAK or BAK1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:75 Cells:% prod#:% Target#:632 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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