Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
6703- DFC,    Molecular docking of anti-inflammatory drug diclofenac with metabolic targets: Potential applications in cancer therapeutics.
- Analysis, Var, NA
*Inflam?, *COX1↓, *COX2↓, GLUT1↓, MCT4↓, LDHA↓, ABCG2↓, MDM2↓, MRP1/ABCC1↓, SOD2↓, Myc↓, β-catenin/ZEB1↓, VEGF↓, IKKα↓, cJun↓, E2Fs↓,
2196- SK,    Research progress in mechanism of anticancer action of shikonin targeting reactive oxygen species
- Review, Var, NA
*ALAT↓, *AST↓, *Inflam?, *EMT↑, ROS?, TrxR1↓, PERK↑, eIF2α↑, ATF4↑, CHOP↑, IRE1↑, JNK↑, eff↝, DR5↑, Glycolysis↓, PKM2↓, ChemoSen↑, GPx4↓, HO-1↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GPx4↓, 1,   HO-1↑, 1,   ROS?, 1,   SOD2↓, 1,   TrxR1↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Glycolysis↓, 1,   LDHA↓, 1,   MCT4↓, 1,   PKM2↓, 1,  

Cell Death(tgid=5) ⓘ

DR5↑, 1,   JNK↑, 1,   MDM2↓, 1,   Myc↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↑, 1,   eIF2α↑, 1,   IRE1↑, 1,   PERK↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↓, 1,  

Migration(tgid=13) ⓘ

β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↑, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IKKα↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   ChemoSen↑, 1,   eff↝, 1,   MRP1/ABCC1↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Myc↓, 1,  
Total Targets: 29

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2↓, 1,   Inflam?, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,  
Total Targets: 7

Scientific Paper Hit Count for: Inflam, inflammation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:953  State#:%  Dir#:0
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