Siegesbeckia glabrescens / Inflam Cancer Research Results

GSL, Siegesbeckia glabrescens: Click to Expand ⟱

Features:

Germacranolide sesquiterpene lactone (GSL) was isolated from Siegesbeckia glabrescens as an inhibitor of Gli.

Inflam, inflammation: Click to Expand ⟱

Source:

Type:

Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.

Scientific Papers found: Click to Expand⟱

7111-

GSL,

In vitro antiinflammatory activity of a new sesquiterpene lactone isolated from Siegesbeckia glabrescens

NA,

Nor,

*NO↓, *PGE2↓, *iNOS↓, *COX2↓, *NF-kB↓, *Inflam↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Cell Death(tgid=5) ⓘ

iNOS↓, 1,

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 1, Inflam↓, 1, NF-kB↓, 1, PGE2↓, 1,
Total Targets: 6

Scientific Paper Hit Count for: Inflam, inflammation

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells