Radiotherapy/Radiation / SOX2 Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱

Features:

Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.

SOX2, SOX2: Click to Expand ⟱

Source:

Type:

SOX2 is a transcription factor that plays a crucial role in the development and maintenance of various cell types, including stem cells and progenitor cells. In the context of cancer, SOX2 has been found to be overexpressed in several types of tumors, including lung, breast, and esophageal cancers.
Overexpressed in: Lung, Breast, Esophageal, Prostate, GBM, CRC.

Scientific Papers found: Click to Expand⟱

2715-

BBR,

Rad,

Berberine Can Amplify Cytotoxic Effect of Radiotherapy by Targeting Cancer Stem Cells

in-vitro,

BC,

MCF-7

tumCV↓, OCT4↓, SOX2↓, RadioS↑, CSCs↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Transcription & Epigenetics ⓘ

tumCV↓, 1,

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1, OCT4↓, 1, SOX2↓, 1,

Drug Metabolism & Resistance ⓘ

RadioS↑, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: SOX2, SOX2

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells