Radiotherapy/Radiation / EIF4E Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱
Features:
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
EIF4E, eukaryotic translation initiation factor 4E: Click to Expand ⟱
Source:
Type: protein
EIF4E: a protein that plays a crucial role in the regulation of protein synthesis, particularly in the translation of mRNAs involved in cell growth, proliferation, and survival.
EIF4E overexpressed in: breast, lung, colon, and prostate cancer.
Scientific Papers found: Click to Expand⟱
5662- BNL,  Rad,    Role of Borneol Induced Autophagy in Enhancing Radiosensitivity of Malignant Glioma
- vitro+vivo, GBM, NA
RadioS↑, Beclin-1↑, Hif1a↓, mTORC1↓, EIF4E↓, TumAuto↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   TumAuto↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EIF4E↓, 1,   mTORC1↓, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,  

Drug Metabolism & Resistance ⓘ

RadioS↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: EIF4E, eukaryotic translation initiation factor 4E
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:201  Target#:716  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page