Dose Cancer Research Results
Dose, Dosage: Click to Expand ⟱
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| Type: |
Drug dosage vs efficacy, and actual dosage number of research papers.
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Scientific Papers found: Click to Expand⟱
Dose↓, Remission↑,
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in-vitro, |
BC, |
MCF7 |
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- |
in-vitro, |
Nor, |
MCF10 |
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- |
in-vitro, |
BC, |
MDA-MB-231 |
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- |
in-vitro, |
BC, |
BT549 |
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- |
in-vivo, |
BC, |
MDA-MB-231 |
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ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
| - |
in-vitro, |
Lung, |
A549 |
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- |
in-vitro, |
BC, |
MCF7 |
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- |
in-vitro, |
BC, |
MDA-MB-231 |
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Dose↓, selectivity↑,
| - |
in-vitro, |
BC, |
MDA-MB-231 |
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- |
in-vitro, |
BC, |
T47D |
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- |
in-vitro, |
Nor, |
MCF10 |
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TumCD↑, DNAdam↑, *antiOx↑, *AntiTum↑, Inflam↓, tumCV↓, Bcl-2↓, Apoptosis↓, selectivity↑, eff↑, Dose↓,
Inflam↓, IL6↓, MCP1/CCL2↓, COX2/PTGS2↓, PGE2↓, MMP2↓, MMP9↓, DNAdam↑, eff↝, Telomerase↓, Bcl-2↓, AMPK↑, ROS↑, MMP↓, ATP↓, p‑mTORC1↓, p‑S6K↓, ERK↓, PI3K↓, PTEN↑, Akt↓, Raf↓, MEK↓, Dose↓, Dose↑, selectivity↑, TumCCA↑, eff↑, EGFR↓, Glycolysis↓, Dose?, p27/CDKN1B↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycE/CCNE↓, Bax:Bcl2↑, Casp3↑, Casp9↑, VEGFR2/KDR/Flk1↓, ChemoSen↑, eff↑, eff↑, PGE2↓, JAK2↓, STAT3↓, CXCR4↓, CCR7↓, uPA↓, CSCs↓, EMT↓, Diff↓, CD133↓, Nestin↓, n-MYC↓, NOTCH↓, SOX2↓, Hif1a↓, VEGF↓, RadioS↑,
Risk↓, Dose↓, eff↝,
*cognitive↑, *eff↑, *Dose↝, *Dose↓,
TCA↓, T-Cell↝, Glycolysis↓, PKM2↓, PFK2?, SDH↓, PDH↓, β-oxidation↓, CPT1A↓, FASN↑, Casp3↑, Casp2↑, Casp8↑, Casp9↑, cl‑PARP↑, Hif1a↓, GLUT1↓, angioG↓, Ca+2↓, ROS↓, eff↓, Dose↓, eff↑, Mcl-1↓, HK2↓, IGF-1R↓, PTEN↑, citrate↓, Dose∅, eff↑, eff↑, eff↑, eff↑,
| - |
in-vitro, |
BC, |
MCF7 |
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- |
in-vitro, |
BC, |
MDA-MB-231 |
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angioG↓, tumCV↓, Dose↓, ROS↑,
MMPs↓, MMP2↓, MMP9↓, MMP14↓, TumCI↓, TumCMig↓, Dose↓,
Src↓, ABL1↓, BioAv↑, TumCG↓, Dose↓, TumCA↓, TumCMig↓, TumCI↓,
eff↑, Dose↓, Risk↓,
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vitro+vivo, |
Melanoma, |
B16-BL6 |
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- |
in-vitro, |
BC, |
E0771 |
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- |
in-vitro, |
BC, |
4T1 |
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TumCP↓, TumCMig↓, TumCCA↑, CD155↓, Dose↓, other↝, TumCG↓,
*Dose↓, Apoptosis↑, DNAdam↑, mtDam↑,
*MusCon↓, *Dose↓, *eff↑, *Temp↝,
MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,
*Dose↓, *toxicity↓,
*Dose↓, *Dose↑, *toxicity↑, *creat↑, *Dose↑, *other?,
*Dose↝, toxicity↝, Bil∅, toxicity↝, Dose↓,
*eff↑, *uricA↓, *toxicity↓, *antiOx↑, *Inflam↓, *Dose↝, *Dose↝, *Dose↝, *toxicity↓, *Dose↓, *ROS↓,
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose↓, *Dose↝, *eff↑, *ROS↓, *RNS↓, *NRF2↑, *HO-1↑, *Fenton↓, *NLRP3↓, *NADPH↓, *NOX4↓, *NOX↓, *MPO↓, *NF-kB↓, *TNF-α↓, *IL6↓, *IL1β↓, *HMGB1↓, *IL4↑, *IL10↑, *M2 MC↑, *Treg lymp↝, *Bcl-2↑, *Bcl-xL↑, *PI3K↑, *Akt↑, *JAK2↑, *STAT3↑, *Dose↑, *CD4+↑, *CD25+↑, *FOXP3↑, *MDA↓, *SOD↑, *Catalase↑, *Casp3↓, *Casp9↓, *TBARS↓, *SpO2↑, *VitE↓, *OS↑, *Weight↑, *DNAdam↓, *PGE2↓, *MCP1/CCL2↓, *lipid-P↓, *TumCP↓, *tumCV↓, *TumCMig↓, *TumCI↓, TumW↓, TumVol↓, selectivity↑, QoL↑, ChemoSen↑, chemoP↑, radioP↑, ROS↑, NLRP3↑, Casp3↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓,
*neuroP↑, *GSH↑, *HO-1↑, *NADPH↑, *Trx1↑, *TrxR1↑, *NRF2↑, *ROS↓, *antiOx↑, *BBB↑, Dose↓,
*Dose↓, *eff↑, *BP↓,
ROS↑, Dose↓, Dose↑, antiOx↑, P450↓, TNF-α↓, IL1β↓, IL12↓,
| - |
Review, |
AD, |
NA |
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- |
Review, |
Stroke, |
NA |
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- |
Review, |
Park, |
NA |
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*neuroP↑, *Aβ↓, *p‑tau↓, *ROS↓, *Inflam↓, *AChE↓, *BBB↑, *memory↑, *hepatoP↑, *Imm↑, *hyperG↓, *AntiCan↑, *eff↑, *Stroke↓, *BACE/β-secretase↓, *PI3K↓, *Akt↓, *mTOR↓, *Dose↓,
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in-vitro, |
HCC, |
HUH7 |
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- |
in-vivo, |
HCC, |
NA |
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TumCG↓, toxicity↓, OS↑, TSP-1↑, Dose↓, Dose↓,
| - |
in-vitro, |
BC, |
4T1 |
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- |
in-vitro, |
BC, |
MCF7 |
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ChemoSen↑, TRPC1↑, Dose↓, selectivity↑,
ROS↑, Apoptosis↑, TumAuto↑, TumCP↓, TumCMig↓, TumCI↓, EMT↓, Dose↓, selectivity↑, Akt↓, eff↓, BAX↑, cl‑Casp3↑, cl‑PARP↑, Bcl-2↓,
Risk↓, AntiCan↑, TumCP↓, TumMeta↓, ChemoSen↑, *BioAv↑, *other↝, *Dose↝, Dose↓, *BioAv↑, *Dose↝, *Half-Life↝, *toxicity↝, GSH↓, ROS↑, CYP1A1↑, CYP1A2↑, P450↓, CYP2E1↑, CYP3A4↓, CYP2A3/CYP2A6↓, *ROS↓, *GPx1↑, *SOD1↑, *SOD2↑, Akt↓, EGFR↓, HER2/EBBR2↓, P53↑, Telomerase↓, selectivity↑, MMP↓, Cyt‑c↑, Apoptosis↑, DR4↑, Fas↑, XIAP↓, survivin↓, TumAuto↑, Hif1a↓, angioG↓, MMPs↓, ERK↓, NF-kB↓, EMT↓, TumCI↓, TumCMig↓, Glycolysis↓, ATP↓, selectivity↑, *antiOx↑, Dose↝, other↝, OCR↓, GSH↓, ITGB1↓, ITGB6↓, ChemoSen↑,
*SIRT1↑, *cognitive↑, *Aβ↓, *Inflam↓, *neuroP↑, memory↑, Dose↓, NAD↑,
*AMPK↑, *P21↑, *Dose↓, *chemoPv↑,
*BP↓, *Dose↓, eff↑,
Dose↑, eff↓, Dose↓,
Risk↓, selm↑, Dose↓, antiOx↑, Dose↑, Dose↝,
Dose↓, other↝,
*selenoP↑, *Dose↓, Risk↓, *toxicity↝, Dose↑, chemoP↑, radioP↑,
tumCV↓, selectivity↑, DNAdam↑, ROS↑, *ROS∅, Dose↓, TumCG↓,
*memory↑, *p‑tau↓, *cognitive↑, *Dose↝, *Dose↓, *Aβ↓, *other↝, *eff↑, *eff↑,
| - |
Study, |
AD, |
NA |
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- |
Study, |
Park, |
NA |
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*Risk↑, *Dose↝, *Dose↓, *other↝,
*antiOx↑, *neuroP↑, *Dose↓, *cognitive↑, *other↝,
Showing Research Papers: 1 to 41 of 41
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 41
Pathway results for Effect on Cancer / Diseased Cells:
NA, unassigned(tgid=0) ⓘ
CD155↓, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 2, Bil∅, 1, CYP1A1↑, 1, CYP2E1↑, 1, GSH↓, 2, ROS↓, 1, ROS↑, 9,
Metal & Cofactor Biology(tgid=2) ⓘ
selm↑, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ABL1↓, 1, ATP↓, 2, ETC↝, 1, MEK↓, 1, MMP↓, 3, mtDam↑, 1, OCR↓, 1, Raf↓, 1, SDH↓, 1, XIAP↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
AMPK↑, 1, citrate↓, 1, CPT1A↓, 1, CYP3A4↓, 1, FASN↑, 1, Glycolysis↓, 3, HK2↓, 1, NAD↑, 1, PDH↓, 1, PFK2?, 1, PKM2↓, 1, p‑S6K↓, 1, TCA↓, 1, β-oxidation↓, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 3, Apoptosis↓, 1, Apoptosis↑, 3, BAX↑, 1, Bax:Bcl2↑, 1, Bcl-2↓, 3, Casp2↑, 1, Casp3↑, 4, cl‑Casp3↑, 1, Casp8↑, 1, Casp9↑, 4, Cyt‑c↑, 2, DR4↑, 1, Fas↑, 2, Mcl-1↓, 1, MOMP↑, 1, p27/CDKN1B↑, 1, survivin↓, 1, Telomerase↓, 2, TumCD↑, 2,
Kinase & Signal Transduction(tgid=6) ⓘ
HER2/EBBR2↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
other↝, 7, tumCV↓, 3,
Protein Folding & ER Stress(tgid=8) ⓘ
ER Stress↑, 1, UPR↑, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
TumAuto↑, 2,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↑, 6, P53↑, 1, cl‑PARP↑, 2, γH2AX↑, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
CDK2↓, 1, CDK4↓, 1, cycD1/CCND1↓, 1, cycE/CCNE↓, 1, TumCCA↑, 2,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
CD133↓, 2, CD44↓, 1, CSCs↓, 2, Diff↓, 1, EMT↓, 3, ERK↓, 2, IGF-1R↓, 1, p‑mTORC1↓, 1, n-MYC↓, 1, Nestin↓, 1, NOTCH↓, 1, PI3K↓, 1, PTEN↑, 2, SOX2↓, 1, Src↓, 1, STAT3↓, 1, TumCG↓, 5, Wnt↓, 1,
Migration(tgid=13) ⓘ
Ca+2↓, 1, Ca+2↑, 1, ITGB1↓, 1, ITGB6↓, 1, MMP14↓, 1, MMP2↓, 2, MMP9↓, 2, MMPs↓, 2, TRPC1↑, 1, TSP-1↑, 1, TumCA↓, 1, TumCI↓, 4, TumCMig↓, 5, TumCP↓, 3, TumMeta↓, 1, uPA↓, 1, β-catenin/ZEB1↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
angioG↓, 3, EGFR↓, 2, EPR↑, 1, Hif1a↓, 3, VEGF↓, 2, VEGFR2/KDR/Flk1↓, 1,
Barriers & Transport(tgid=15) ⓘ
GLUT1↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CCR7↓, 1, COX2/PTGS2↓, 1, CXCR4↓, 1, HMGB1↓, 1, IL12↓, 1, IL1β↓, 1, IL6↓, 1, Imm↑, 1, Inflam↓, 2, JAK2↓, 1, MCP1/CCL2↓, 1, NF-kB↓, 1, PGE2↓, 2, T-Cell↝, 1, TNF-α↓, 1,
Protein Aggregation(tgid=19) ⓘ
NLRP3↑, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↑, 1, BioAv↝, 2, ChemoSen↑, 6, CYP1A2↑, 1, CYP2A3/CYP2A6↓, 1, Dose?, 1, Dose↓, 27, Dose↑, 6, Dose↝, 6, Dose∅, 1, eff↓, 4, eff↑, 15, eff↝, 2, P450↓, 2, RadioS↑, 2, selectivity↑, 12,
Clinical Biomarkers(tgid=22) ⓘ
Bil∅, 1, EGFR↓, 2, HER2/EBBR2↓, 1, IL6↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 1, chemoP↑, 2, memory↑, 1, OS↑, 2, QoL↑, 1, radioP↑, 2, Remission↑, 2, Risk↓, 5, toxicity↓, 2, toxicity↝, 2, TumVol↓, 1, TumW↓, 1,
Total Targets: 158
Pathway results for Effect on Normal Cells:
NA, unassigned(tgid=0) ⓘ
SpO2↑, 1, Stroke↓, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 6, Catalase↑, 1, Fenton↓, 1, GPx1↑, 1, GSH↑, 1, HO-1↑, 2, hyperG↓, 1, lipid-P↓, 1, MDA↓, 1, MPO↓, 1, NOX4↓, 1, NRF2↑, 2, RNS↓, 1, ROS↓, 5, ROS∅, 1, selenoP↑, 1, SOD↑, 1, SOD1↑, 1, SOD2↑, 1, TBARS↓, 1, Trx1↑, 1, TrxR1↑, 1, uricA↓, 1, VitE↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
AMPK↑, 1, NADPH↓, 1, NADPH↑, 1, SIRT1↑, 2,
Cell Death(tgid=5) ⓘ
Akt↓, 1, Akt↑, 1, Apoptosis↓, 1, Bcl-2↑, 1, Bcl-xL↑, 1, Casp3↓, 1, Casp9↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
other?, 1, other↝, 4, tumCV↓, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↓, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
P21↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
mTOR↓, 1, PI3K↓, 1, PI3K↑, 1, STAT3↑, 1,
Migration(tgid=13) ⓘ
Treg lymp↝, 1, TumCI↓, 1, TumCMig↓, 1, TumCP↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
Hif1a↑, 1,
Barriers & Transport(tgid=15) ⓘ
BBB↑, 2,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CD25+↑, 1, CD4+↑, 1, FOXP3↑, 1, HMGB1↓, 1, IL10↑, 1, IL1β↓, 1, IL4↑, 1, IL6↓, 1, Imm↑, 1, Inflam↓, 4, JAK2↑, 1, M2 MC↑, 1, MCP1/CCL2↓, 1, NF-kB↓, 1, PGE2↓, 1, TNF-α↓, 1,
Cellular Microenvironment(tgid=17) ⓘ
NOX↓, 1, Temp↝, 1,
Synaptic & Neurotransmission(tgid=18) ⓘ
AChE↓, 1, p‑tau↓, 2,
Protein Aggregation(tgid=19) ⓘ
Aβ↓, 3, BACE/β-secretase↓, 1, NLRP3↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↑, 2, Dose↓, 15, Dose↑, 3, Dose↝, 10, eff↑, 8, Half-Life↝, 1,
Clinical Biomarkers(tgid=22) ⓘ
BP↓, 2, creat↑, 1, IL6↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiAge↑, 1, AntiCan↑, 1, AntiTum↑, 1, chemoPv↑, 1, cognitive↑, 4, hepatoP↑, 1, memory↑, 2, MusCon↓, 1, neuroP↑, 4, OS↑, 1, Risk↑, 1, toxicity↓, 3, toxicity↑, 1, toxicity↝, 2, Weight↑, 1,
Total Targets: 99
Scientific Paper Hit Count for: Dose, Dosage
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1114 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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