IGFBP1 Cancer Research Results

IGFBP1, Insulin-like Growth Factor Binding Protein 1: Click to Expand ⟱
Source:
Type:
IGFBP1 is one of several binding proteins that modulate IGF (insulin-like growth factor) availability and signaling, which can affect cell proliferation, apoptosis, and cellular metabolism.

– In some cohorts, higher circulating or tissue levels of IGFBP1 have been associated with a less aggressive disease phenotype and better overall survival.

– Conversely, in other studies, low IGFBP1 levels have been linked with a more advanced disease state, suggesting that IGFBP1 may serve as an indicator of preserved liver function or a less aggressive tumor biology.
Scientific Papers found: Click to Expand⟱
5061- Ex,    Role of physical exercise in modulating the insulin-like growth factor system for improving breast cancer outcomes: A meta-analysis
- Review, BC, NA
IGF-2↓, IGFBP1↓, HOMA↓, glucose∅, IGF-1∅, eff↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

glucose∅, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1∅, 1,   IGF-2↓, 1,   IGFBP1↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Clinical Biomarkers ⓘ

HOMA↓, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: IGFBP1, Insulin-like Growth Factor Binding Protein 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1189  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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