cellD Cancer Research Results

cellD, cell Death: Click to Expand ⟱

Source:

Type:

Cell Death

Scientific Papers found: Click to Expand⟱

2034-

PB,

Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress

in-vitro,

Nor,

SH-SY5Y

*ER Stress↓, Moreover, these compounds protected cells against ER stress-induced neuronal cell death.
*ChemChap↓, The cytoprotective effect correlated with the in vitro chemical chaperone activity.
*cytoP↑,
*cellD↓, 3-PPA and 4-PBA significantly suppressed neuronal cell death caused by ER stress induced by the overexpression of Pael-R
*neuroP↑, These results suggest that terminal aromatic substituted fatty acids are potential candidates for the treatment of neurodegenerative diseases.

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Cell Death ⓘ

cellD↓, 1,

Protein Folding & ER Stress ⓘ

ChemChap↓, 1, ER Stress↓, 1,

Functional Outcomes ⓘ

cytoP↑, 1, neuroP↑, 1,
Total Targets: 5

Scientific Paper Hit Count for: cellD, cell Death

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells