Inf Cancer Research Results

Inf, Infection: Click to Expand ⟱
Source:
Type:
An infection occurs when a microorganism—such as a bacterium, virus, fungus, or parasite—enters the body, establishes itself, and begins to multiply.

Oncogenic Viruses and Chronic Infections:
Certain viruses are known as oncogenic (cancer-causing) viruses. For example:
-Human Papillomavirus (HPV): Certain strains of HPV can lead to cervical cancer, as well as other cancers such as oropharyngeal and anal cancers.
-Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV): These viruses can cause chronic liver infections that may progress to liver cirrhosis and ultimately hepatocellular carcinoma (liver cancer).
-Epstein-Barr Virus (EBV): This virus is linked to several cancers, including Hodgkin lymphoma, Burkitt lymphoma, and nasopharyngeal carcinoma.

-Some infections directly or indirectly weaken the immune system, reducing its ability to detect and eliminate emerging cancer cells.
Scientific Papers found: Click to Expand⟱
4365- AgNPs,    Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview
- Review, Var, NA
ROS↑, the most remarkable mechanistic mode of AgNP-based antimicrobial effects is represented by their adhesion to microbial cells, ROS and free-radical generation, microbial wall piercing and penetration inside cells, and modulation and modification of mi
*toxicity↓, high intrinsic antimicrobial efficiency and non-toxic nature
*Bacteria↓,
*Inf↓, silver-based compounds and materials were used for the unconventional and effective control of distinctive infections
*Diff↑, Previous studies reported that AgNPs naturally improve the differentiation process of MC3T3-1 pre-osteoblast cells and subsequent bone-like tissue mineralization,
*eff↑, studies showed that AgNP-implanted titanium displayed improved antibacterial ability,
RadioS↑, making them suitable candidates for detection and dose-enhancement purposes in X-ray irradiation applications
selectivity↑, selective uptake into cancerous cells, AgNP-derived scattered light can be used for imaging purposes, whereas absorbed light can be used for selective hyperthermia

2051- PB,    Beneficial Effects of Sodium Phenylbutyrate Administration during Infection with Salmonella enterica Serovar Typhimurium
- in-vivo, Inf, NA
*Inf↓, PBA has a previously undiscovered protective role in host mucosal defense during infection
*GutMicro↑, PBA to Taconic mice resulted in the increase of intestinal Lactobacillales and segmented filamentous bacteria (SFB)
*IL17↑, increase of interleukin 17 (IL-17) production by intestinal cells
*Inflam↓, lower levels of inflammation
*ER Stress↓, PBA also plays a role in the reduction of endoplasmic reticulum (ER) stress caused by the unfolded protein response (UPR), thereby suppressing oxidative stress in several animal models
*ROS↓,
*OS↑, PBA was shown to increase the life span of flies, which was associated with both a global increase in histone acetylation and a marked alteration of gene expression
*Bacteria↓, PBA administration was shown to inhibit the growth of Helicobacter pylori and Escherichia coli
*Neut↑, these results indicated that PBA treatment reduces intestinal inflammation, the recruitment of neutrophils to the gut
*toxicity↓, PBA, which has been safely used in children and adults for the past 20 years to treat urea cycle disorders


Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Drug Metabolism & Resistance ⓘ

RadioS↑, 1,   selectivity↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

ROS↓, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

Diff↑, 1,  

Immune & Inflammatory Signaling ⓘ

IL17↑, 1,   Inflam↓, 1,   Neut↑, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 1,  

Functional Outcomes ⓘ

OS↑, 1,   toxicity↓, 2,  

Infection & Microbiome ⓘ

Bacteria↓, 2,   Inf↓, 2,  
Total Targets: 12

Scientific Paper Hit Count for: Inf, Infection
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1241  State#:%  Dir#:1
  wNotes=on  sortOrder:rid,rpid

 

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