creat Cancer Research Results
creat, creatinine: Click to Expand ⟱
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Creatinine is fundamentally a metabolic waste product derived from creatine phosphate in muscle. Its blood levels are routinely used as a clinical biomarker to assess kidney function rather than a direct regulator of oncogenic processes.
Creatinine is a primary marker used to estimate the glomerular filtration rate (GFR).
-Elevated creatinine can be a sign of compromised kidney vascular function.
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Scientific Papers found: Click to Expand⟱
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Review, |
AD, |
NA |
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Review, |
Var, |
NA |
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- |
Review, |
Park, |
NA |
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- |
Review, |
Stroke, |
NA |
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*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2/KDR/Flk1↓, p‑FAK↓,
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
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in-vitro, |
Nor, |
NRK52E |
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in-vivo, |
NA, |
NA |
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*RenoP↑, *hepatoP↑, *creat↓, *BUN↓, *uricA↓, *Apoptosis↓, *α-SMA↓,
*glucose↓, *creat↓, *SOD↑, *MMP↑, *ROS↓,
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Review, |
Var, |
NA |
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Review, |
Park, |
NA |
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Review, |
AD, |
NA |
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AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE/β-secretase↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2/PTGS2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↑, *MMP13↓,
*lipid-P↓, *MDA↓, *antiOx↑, *Inflam↑, RenoP↑, hepatoP↑, *ALAT↓, AST↓, creat↓, chemoPv↑, Cyt‑c↑, FADD↑, P53↑,
*RenoP↑, *creat↓, *Inflam↓, *TNF-α↓, *IL1β↓, *COX2/PTGS2↓, *ROS↓, *NRF2↑, *GastroP↑, *TLR4↓, *NF-kB↓, *AP-1↓, *Sepsis↓,
*hepatoP↑, *AST↓, *ALAT↓, *ALP↓, *Bil↓, *creat↓, *TOS↑,
*antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Cyt‑c↓, *DNAdam↓, *GSH↑, *SOD↑, *Albumin↝, *creat↓, *BUN↓, *RenoP↑, *lipid-P↓, *TNF-α↓, *Casp3↓, *Casp9↓, *chemoP↑,
AST↓, ALAT↓, ALP↓, Bil↝, creat↓, uricA↓, ChemoSen↑, chemoP↑,
*antiOx↑, *Inflam↓, *antiNeop↑, *cardioP↑, *Bacteria↓, *AST↓, *ALAT↓, *ALP↓, *lipid-P↓, *GSH↑, *Catalase↑, *GPx↑, *GSTs↑, *Urea↓, *creat↓, tumCV↓, TumCCA↑, i-Ca+2↑, CDK1↑, Casp3↑, Casp8↑, Casp9↑, MMP↓, ROS↑, MMPs↓, *GastroP↑, *hepatoP↑, *ROS↓, *AChE↑,
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Review, |
Var, |
NA |
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Review, |
IBD, |
NA |
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Review, |
Stroke, |
NA |
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- |
Review, |
Sepsis, |
NA |
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- |
Review, |
AD, |
NA |
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Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, eff↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑,
RenoP↑, BHB↑, HMGCS2↑, chemoP↑, *IL2↓, *IL6↓, *MCP1/CCL2↓, *TNF-α↓, *KeyT↝, *Inflam↓, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *PGC-1α↑, *BUN↓, *creat↓,
*ROS↓, *antiOx↑, *Inflam↓, *chemoP↑, AntiCan↑, ChemoSen↑, chemoP↑, *BUN↓, *creat↓, *TUNEL↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *BNP↓, *AST↓, *ALAT↓, *TNF-α↓, *IL1β↓, *IL6↓, *Casp3↓, *Casp9↓, *GPx↑, *E-cadherin↑, *Vim↓, *α-SMA↓, *COL1↓, *cardioP↑, *hepatoP↑, *p‑mTOR↓, *EMT↓, eff∅, *LPS↓, *TLR4↓, radioP↑,
*creat↓, *RenoP↑,
RenoP↑, *BUN↓, *creat↓, *TNF-α↓, *IL1β↓, *IL6↓, *MDA↓, *ROS↓, *NF-kB↓, *NRF2↑, *HO-1↑,
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Review, |
Var, |
NA |
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- |
Review, |
AD, |
NA |
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- |
Review, |
Stroke, |
NA |
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*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
| - |
Review, |
Var, |
NA |
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- |
Review, |
AD, |
NA |
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*antiOx↑, *ROS↓, *hepatoP↑, *lipid-P↓, *ALAT↓, *AST↓, *ALP↓, *creat↓, *RenoP↑, NF-kB↓, ChemoSen↑, *memory?,
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Review, |
Nor, |
NA |
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- |
NA, |
AD, |
NA |
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- |
NA, |
Diabetic, |
NA |
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- |
NA, |
Stroke, |
NA |
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- |
NA, |
LiverDam, |
NA |
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- |
NA, |
Park, |
NA |
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*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
*antiOx↑, *Thiols↑, *GSH↑, *TAC↑, *SOD↑, *GPx↑, *Catalase↑, *ALP↓, *ALAT↓, *AST↓, *creat↓, *BUN↓, *H2O2↓, *MDA↓, *ROS↓, cardioP↑, hepatoP↑, neuroP↑,
chemoP↑, creat↓, BUN↓,
*toxicity↓, *Bacteria↓, ROS↑, MMP↓, ER Stress↑, P53↑, Apoptosis↑, Casp9↑, DNAdam↑, TumCCA↑, eff↑, Catalase↓, SOD↓, GSH↓, selectivity↓, selectivity↑, PCNA↓, eff↑, *ALAT↓, *AST↓, *ALP↓, *creat↓, *Inflam↓, *toxicity↓, selectivity↑,
*NRF2↑, *HO-1↑, *creat↓, *BUN↓, *RenoP↑, *MDA↓, *TNF-α↓, *IL1β↓, *Cyt‑c↓, *Casp3↓, *GSTs↓, *GSH↑, *GPx4↑, *SOD↑, *GSR↓, *Ferroptosis↓,
*creat↓, *ROS↓, *other↑, *MDA↓, *other↑, *Inflam↓,
*antiOx↑, *RenoP↑, *hepatoP↑, *SOD↑, *GSH↑, *ROS↓, *lipid-P↓, ALAT↓, creat↓,
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in-vitro, |
Nor, |
HEK293 |
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in-vivo, |
NA, |
NA |
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*creat↓, *TNF-α↓, *IL6↓, *MRP↓, *GFR↑, *mt-ATPase↑, *p‑Akt↑, *NRF2↑, *HO-1↑, *Casp3↓, *NF-kB↓, *RenoP↑,
Showing Research Papers: 1 to 26 of 26
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 26
Pathway results for Effect on Cancer / Diseased Cells:
NA, unassigned(tgid=0) ⓘ
BHB↑, 1, CD47↓, 1, HMGCS2↑, 1, miR-124-3p↓, 1, PFS↑, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
Bil↝, 1, Catalase↓, 1, GSH↓, 2, ROS↓, 1, ROS↑, 3, SOD↓, 1, uricA↓, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
MMP↓, 2, PGC-1α↑, 1, XIAP↓, 2,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ALAT↓, 2, BUN↓, 1, SCD1↓, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 3, Apoptosis↑, 3, Bak↓, 1, BAX↑, 1, Bcl-2↓, 2, BID↑, 1, Casp12↑, 1, Casp3↑, 3, Casp8↑, 3, Casp9↑, 4, Cyt‑c↑, 3, FADD↑, 1, Fas↑, 2, IAP2/BIRC3↓, 1, p38↑, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
HER2/EBBR2↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
EZH2↓, 1, tumCV↓, 1,
Protein Folding & ER Stress(tgid=8) ⓘ
ER Stress↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
CHK1↓, 1, DNAdam↑, 1, P53↑, 4, PARP↑, 1, PCNA↓, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
CDK1↑, 1, CDK4↓, 1, CycB/CCNB1↓, 1, P21↑, 1, TumCCA↑, 4,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
FGF↓, 1, PI3K↓, 1, STAT3↓, 1,
Migration(tgid=13) ⓘ
i-Ca+2↑, 1, CEA↓, 1, p‑FAK↓, 1, MALAT1↓, 1, MMPs↓, 1, TIMP2↑, 1, TumCI↓, 1, TumCMig↓, 2, TumCP↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
EGFR↑, 1, Hif1a↓, 2, VEGF↓, 1, VEGFR2/KDR/Flk1↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX2/PTGS2↓, 1, IL8↓, 1, NF-kB↓, 1, NF-kB↑, 1, NK cell↑, 1, PGE2↓, 1,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
CDK6↑, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
ChemoSen↑, 4, Dose↝, 2, eff↑, 4, eff∅, 1, RadioS↑, 1, selectivity↓, 1, selectivity↑, 3,
Clinical Biomarkers(tgid=22) ⓘ
ALAT↓, 2, ALP↓, 1, AST↓, 2, Bil↝, 1, CEA↓, 1, creat↓, 4, EGFR↑, 1, EZH2↓, 1, HER2/EBBR2↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 3, cardioP↑, 2, chemoP↑, 6, chemoPv↑, 1, hepatoP↑, 2, neuroP↑, 1, NP/CIPN↓, 1, QoL↑, 1, radioP↑, 2, RenoP↑, 3, TumVol↓, 1,
Infection & Microbiome(tgid=24) ⓘ
CD8+↑, 2,
Total Targets: 98
Pathway results for Effect on Normal Cells:
NA, unassigned(tgid=0) ⓘ
AntiBio↑, 2, compII↑, 1, Stroke↓, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 13, Bil↓, 1, Catalase↑, 7, Ferroptosis↓, 1, GPx↑, 4, GPx4↑, 1, GSH↑, 9, GSR↓, 1, GSTs↓, 1, GSTs↑, 3, H2O2↓, 1, HO-1↑, 6, Keap1↓, 1, Keap1↑, 1, lipid-P↓, 8, MDA↓, 11, MFN2↑, 1, MPO↓, 2, NOX4↓, 1, NQO1↑, 1, NRF2↑, 9, ROS↓, 17, SOD↑, 11, TAC↑, 2, TBARS↓, 2, Thiols↑, 1, TOS↑, 1, uricA↓, 2,
Metal & Cofactor Biology(tgid=2) ⓘ
IronCh↑, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ATP↑, 3, compIII↑, 1, MMP↑, 4, mtDam↓, 1, PGC-1α↑, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ALAT↓, 9, BUN↓, 8, CRM↑, 1, glucose↓, 1, H2S↑, 1, KeyT↝, 1, LDH↓, 2, LDL↓, 1, SIRT1↑, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 1, Akt↑, 1, p‑Akt↑, 1, Apoptosis↓, 3, BAX↓, 1, Bcl-2↑, 1, Casp12↓, 1, Casp3↓, 5, Casp9↓, 2, Cyt‑c↓, 3, Ferroptosis↓, 1, GranB/GZMB↓, 1, iNOS↓, 4, p‑JNK↓, 1, p38↓, 1, TUNEL↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
other↑, 4,
Protein Folding & ER Stress(tgid=8) ⓘ
CHOP/DDIT3↓, 1, p‑eIF2α↓, 1, ER Stress↓, 1, GRP78/BiP↓, 1, XBP-1↓, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
LC3‑Ⅱ/LC3‑Ⅰ↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↓, 2,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
EMT↓, 1, ERK↓, 1, mTOR↓, 1, p‑mTOR↓, 1, PI3K↓, 1, PI3K↑, 1, STAT3↓, 1,
Migration(tgid=13) ⓘ
AP-1↓, 1, APP↓, 1, mt-ATPase↑, 1, COL1↓, 1, E-cadherin↑, 1, MMP13↓, 1, TGF-β↑, 1, VCAM-1↓, 1, Vim↓, 1, α-SMA↓, 2,
Angiogenesis & Vasculature(tgid=14) ⓘ
ATF4↓, 1, NO↓, 2,
Barriers & Transport(tgid=15) ⓘ
BBB↑, 2, GastroP↑, 3, IBI↑, 1, MRP↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CD4+↑, 2, COX2/PTGS2↓, 4, ICAM-1↓, 1, IFN-γ↓, 1, IL1↓, 1, IL10↑, 1, IL1β↓, 8, IL2↓, 1, IL4↓, 1, IL6↓, 9, IL6↑, 1, IL8↓, 1, Imm↑, 2, Inflam↓, 12, Inflam↑, 1, LPS↓, 2, MCP1/CCL2↓, 1, NF-kB↓, 7, PGE2↓, 1, TLR2↓, 1, TLR4↓, 3, TNF-α↓, 13,
Synaptic & Neurotransmission(tgid=18) ⓘ
AChE↓, 1, AChE↑, 1, BChE↓, 1,
Protein Aggregation(tgid=19) ⓘ
Aβ↓, 2, BACE/β-secretase↓, 2, NLRP3↓, 1,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
BNP↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↑, 4, BioAv↝, 2, Dose↝, 3, eff↑, 7, Half-Life↝, 1,
Clinical Biomarkers(tgid=22) ⓘ
ALAT↓, 9, Albumin↝, 1, ALP↓, 5, AST↓, 8, BG↓, 1, Bil↓, 1, BP↓, 2, creat↓, 22, GutMicro↑, 2, IL6↓, 9, IL6↑, 1, LDH↓, 2, Urea↓, 2,
Functional Outcomes(tgid=23) ⓘ
antiNeop↑, 1, antiPs↑, 1, cardioP↑, 7, chemoP↑, 3, cognitive↑, 3, GFR↑, 1, hepatoP↑, 10, memory?, 1, memory↑, 1, motorD↑, 1, neuroP↑, 6, Obesity↓, 1, OS↑, 1, Pain↓, 1, RenoP↑, 12, toxicity↓, 3,
Infection & Microbiome(tgid=24) ⓘ
AntiFungal↑, 1, Bacteria↓, 2, CD8+↑, 1, Sepsis↓, 3,
Total Targets: 160
Scientific Paper Hit Count for: creat, creatinine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1251 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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