BUN Cancer Research Results
BUN, blood urea nitrogen: Click to Expand ⟱
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Blood urea nitrogen (BUN) is a measure of the amount of nitrogen in your blood that comes from the waste product urea. Urea is produced in the liver as a byproduct of protein metabolism and is normally excreted by the kidneys.
-BUN is commonly used as one indicator of kidney function. Elevated BUN levels may suggest that the kidneys are not effectively clearing urea from the blood.
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Scientific Papers found: Click to Expand⟱
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
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in-vitro, |
Nor, |
NRK52E |
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in-vivo, |
NA, |
NA |
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*RenoP↑, *hepatoP↑, *creat↓, *BUN↓, *uricA↓, *Apoptosis↓, *α-SMA↓,
*antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Cyt‑c↓, *DNAdam↓, *GSH↑, *SOD↑, *Albumin↝, *creat↓, *BUN↓, *RenoP↑, *lipid-P↓, *TNF-α↓, *Casp3↓, *Casp9↓, *chemoP↑,
RenoP↑, BHB↑, HMGCS2↑, chemoP↑, *IL2↓, *IL6↓, *MCP1/CCL2↓, *TNF-α↓, *KeyT↝, *Inflam↓, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *PGC-1α↑, *BUN↓, *creat↓,
*ROS↓, *antiOx↑, *Inflam↓, *chemoP↑, AntiCan↑, ChemoSen↑, chemoP↑, *BUN↓, *creat↓, *TUNEL↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *BNP↓, *AST↓, *ALAT↓, *TNF-α↓, *IL1β↓, *IL6↓, *Casp3↓, *Casp9↓, *GPx↑, *E-cadherin↑, *Vim↓, *α-SMA↓, *COL1↓, *cardioP↑, *hepatoP↑, *p‑mTOR↓, *EMT↓, eff∅, *LPS↓, *TLR4↓, radioP↑,
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
RenoP↑, *BUN↓, *creat↓, *TNF-α↓, *IL1β↓, *IL6↓, *MDA↓, *ROS↓, *NF-kB↓, *NRF2↑, *HO-1↑,
*antiOx↑, *Thiols↑, *GSH↑, *TAC↑, *SOD↑, *GPx↑, *Catalase↑, *ALP↓, *ALAT↓, *AST↓, *creat↓, *BUN↓, *H2O2↓, *MDA↓, *ROS↓, cardioP↑, hepatoP↑, neuroP↑,
chemoP↑, creat↓, BUN↓,
*NRF2↑, *HO-1↑, *creat↓, *BUN↓, *RenoP↑, *MDA↓, *TNF-α↓, *IL1β↓, *Cyt‑c↓, *Casp3↓, *GSTs↓, *GSH↑, *GPx4↑, *SOD↑, *GSR↓, *Ferroptosis↓,
*radioP↑, *antiOx↑, *Inflam↓, *DNAdam↓, *lipid-P↓, *selenoP↑, *GPx1↑, *BUN↓,
*RenoP↑, *TAC↑, *ROS↓, *lipid-P↓, *p38↓, *MAPK↓, *NF-kB↓, *NRF2↑, *HO-1↑, *MDA↓, *GPx↑, *GSR↑, *Catalase↑, *BUN↓, *LDH↓, *IL1β↓,
Showing Research Papers: 1 to 12 of 12
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 12
Pathway results for Effect on Cancer / Diseased Cells:
NA, unassigned(tgid=0) ⓘ
BHB↑, 1, HMGCS2↑, 1, MTA1↓, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
Catalase↓, 1, GSH↓, 1, ROS↓, 1, SOD↓, 1, TAC↓, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
MMP↓, 1, XIAP↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
BUN↓, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 1, BAD↑, 1, Bak↑, 1, BAX↑, 1, Bcl-2↓, 1, Bcl-xL↓, 1, Casp3↑, 1, Casp8↑, 1, Cyt‑c↑, 1, Fas↑, 1, p27/CDKN1B↑, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
TumAuto↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
P53↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
mTOR↓, 1, P70S6K↓, 1,
Migration(tgid=13) ⓘ
LRP1↓, 1, MMP2↓, 1, TIMP2↓, 1, TumCI↓, 1, TumCMig↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
VEGF↓, 1,
Barriers & Transport(tgid=15) ⓘ
P-gp/ABCB1↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
IL1β↓, 1, IL6↓, 1, IL8↓, 1, NF-kB↓, 1, PD-L1↓, 1, TLR4↓, 1, TNF-α↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
ChemoSen↑, 1, eff∅, 1,
Clinical Biomarkers(tgid=22) ⓘ
creat↓, 1, IL6↓, 1, PD-L1↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 1, cardioP↑, 1, chemoP↑, 3, hepatoP↑, 1, neuroP↑, 1, radioP↑, 1, RenoP↑, 2,
Total Targets: 52
Pathway results for Effect on Normal Cells:
NA, unassigned(tgid=0) ⓘ
AntiArt↑, 1, antiD↓, 1, Stroke↓, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 5, Catalase↑, 3, Ferroptosis↓, 1, GPx↑, 3, GPx1↑, 1, GPx4↑, 1, GSH↑, 3, GSR↓, 1, GSR↑, 1, GSTs↓, 1, H2O2↓, 1, HO-1↑, 4, lipid-P↓, 3, MDA↓, 6, MFN2↑, 1, NQO1↑, 1, NRF2↑, 5, ROS↓, 6, selenoP↑, 1, SOD↑, 4, TAC↑, 2, Thiols↑, 1, uricA↓, 1,
Metal & Cofactor Biology(tgid=2) ⓘ
IronCh↑, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ATP↑, 1, MMP↑, 1, PGC-1α↑, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ALAT↓, 3, BUN↓, 11, KeyT↝, 1, LDH↓, 1,
Cell Death(tgid=5) ⓘ
Apoptosis↓, 2, Casp3↓, 3, Casp9↓, 2, Cyt‑c↓, 2, Ferroptosis↓, 1, MAPK↓, 1, p38↓, 1, TUNEL↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
AntiThr↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↓, 2,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
EMT↓, 1, p‑mTOR↓, 1,
Migration(tgid=13) ⓘ
COL1↓, 1, E-cadherin↑, 1, PAI-1/SERPINE1↓, 1, Vim↓, 1, α-SMA↓, 2,
Immune & Inflammatory Signaling(tgid=16) ⓘ
IL1β↓, 5, IL2↓, 1, IL6↓, 4, Inflam↓, 5, LPS↓, 1, MCP1/CCL2↓, 1, NF-kB↓, 4, TLR4↓, 1, TNF-α↓, 6,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
BNP↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
eff↑, 2,
Clinical Biomarkers(tgid=22) ⓘ
ALAT↓, 3, Albumin↝, 1, ALP↓, 1, AST↓, 3, creat↓, 8, IL6↓, 4, LDH↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 1, cardioP↑, 2, chemoP↑, 3, hepatoP↑, 3, neuroP?, 1, radioP↑, 1, RenoP↑, 6,
Infection & Microbiome(tgid=24) ⓘ
AntiViral↑, 1, Bacteria↓, 1, Sepsis↓, 2,
Total Targets: 79
Scientific Paper Hit Count for: BUN, blood urea nitrogen
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1338 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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